nucleoside


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nucleoside

 [noo´kle-o-sīd]
any of a class of compounds produced by hydrolysis of nucleotides, consisting of a sugar (a pentose or a hexose) and a purine or pyrimidine base.

nu·cle·o·side (Nuc, N),

(nū'klē-ō-sīd'),
A compound of a sugar (usually ribose or deoxyribose) with a purine or pyrimidine base by way of an N-glycosyl link.

nucleoside

/nu·cleo·side/ (noo´kle-o-sīd″) one of the compounds into which a nucleotide is split by the action of nucleotidase or by chemical means; it consists of a sugar (a pentose) with a purine or pyrimidine base.

nucleoside

(no͞o′klē-ə-sīd′, nyo͞o′-)
n.
Any of various compounds, such as adenosine or guanosine, that consist of a sugar, usually ribose or deoxyribose, linked to a purine or pyrimidine base. Nucleosides are constituents of the nucleotides that make up nucleic acids.

nucleoside

[no̅o̅′klē·əsīd′]
a component of a nucleotide that consists of a nitrogenous base linked to a pentose sugar.

nu·cle·o·side

(nū'klē-ō-sīd)
A compound of a sugar (usually ribose or deoxyribose) with a purine or pyrimidine base.

nucleoside

A molecule compounded of a purine or pyrimidine base attached to a sugar (ribose or deoxyribose). The genetic code in DNA and RNA depends on the order of the nucleosides. A nucleoside is a NUCLEOTIDE without the phosphate group.

nucleoside

a chemical compound in which a nitrogenous base is attached to a sugar. Such a structure occurs in DNA nucleotides where a phosphate group is attached to the deoxyribose sugar of the nucleoside.

nu·cle·o·side

(nū'klē-ō-sīd)
A compound of a sugar (usually ribose or deoxyribose) with a purine or pyrimidine base.

nucleoside (noo´klēəsīd´),

n purine or pyrimidine bases attached to a ribose or deoxyribose.

nucleoside

any of a class of compounds produced by hydrolysis of nucleotides, consisting of a sugar (a pentose or a hexose) and a purine or pyrimidine base.
References in periodicals archive ?
TaciMane[R] gene expression assays for quantification of nucleoside transporters (SLC29A1-A4, SLC28A3) were from Applied Biosystems, Vienna, Austria.
They found that both the human and bacterial transporter use a sodium gradient to import nucleosides and drugs into the cells.
Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients enrolled in the D:A:D study.
With a median follow-up of 112 weeks, the time to virologic failure was significantly shorter in the lopinavir plus two nucleosides arm, compared with the efavirenz plus two nucleosides arm.
Approved March 14, 1997 for the use of alone or in combination with nucleoside analogues for the treatment of HIV infection in selected patients.
The first class of drugs used to treat HIV was the nucleoside analogue reverse transcriptase inhibitors (see Table 1).
They found that the drugs don't stop the enzyme from binding to its target nucleoside.
Pharmaron has been an outstanding supplier of high-quality nucleoside phosphoramidites to Isis.
In the first study to detect an improvement in lipoatrophy after only 24 weeks of treatment modification, 101 patients on zidovudine-inclusive or stavudine-inclusive regimens were randomized to either change their nucleoside to abacavir, switch to a nucleoside-sparing cocktail of ritonavir (Norvir)-boosted lopinavir (Kaletra) plus nevirapine (Viramune), or delay any switch until 24 weeks followed by randomization into one of the two treatment groups.
Both these mutations can cause cross-resistance to other nucleoside analogs.
Although the idea of combining three nucleoside reverse transcriptase inhibitors seemed appealing as a way to spare patients some of the toxicities of nonnucleoside reverse transcriptase inhibitors or protease inhibitors, once-daily triple-nucleoside combinations that lacked zidovudine (AZT) often failed because of gene mutations, which were infrequently seen in the past when nearly every regimen contained AZT, investigators reported at the meeting.
ACH-126,443 (L-Fd4C) nucleoside analog RT inhibitor Phase 1

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