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nucleocytoplasmic ratio

   Also found in: Encyclopedia 0.01 sec.
nucleocytoplasmic ratio,
the ratio of the volume of a nucleus of a cell to the volume of the cytoplasm. The proportion is usually constant for a specific cell type, and an increase is indicative of malignant neoplasms. Also called karyoplasmic ratio, nucleoplasmic ratio.


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7,15) Histologic features of malignant GCTs include necrosis, spindling, vesicular nuclei with prominent nucleoli, high nucleocytoplasmic ratio, cellular pleomorphism, and mitotic figures (>2 mitoses/10 HPF).
Four cases of patients with gastrointestinal granular cell tumors by Cuartas-Hoyos, Urias / Southern Medical Journal
The cells were cuboidal in the hyperplastic and papillary areas, with an increased nucleocytoplasmic ratio, round bland nuclei with low mitotic activity, and inconspicuous nucleoli (Figure 1).
Pulmonary adenocarcinoma simulating malignant mesothelioma. (Case ... by Tang, Ping; Vatsia, Sheel K.; Teichberg, Saul; Kahn, Ellen / Archives of Pathology & Laboratory Medicine
Although occasional cells showed ultrastructural intermediate features between the undifferentiated and glandular cell types (large size and high nucleocytoplasmic ratio but a well-developed endoplasmic reticulum, a prominent Golgi complex, and few secretory granules), in general, there was an abrupt transition between the 2 components.
Epstein-Barr Virus RNA Detection and Glandular Differentiation in ... by Jain, Dhanpat; Parkash, Vinita; Li, Maomi; Gill, James; Crouch, Jill; Howe, Greg; Tallini, Giovanni / Archives of Pathology & Laboratory Medicine
 
 
 
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