nucleic acid test


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Related to nucleic acid test: DNA test

nucleic acid test

any of various tests that use molecular biology techniques to detect and identify microorganisms, including viruses, on the basis of their nucleic acids. It includes culture confirmation tests, which identify organisms grown in culture, and direct tests, which can identify the organisms directly in a specimen. Direct tests can be further subdivided on the basis of whether their target nucleic acids are nonamplified or amplified for the test; the former are based on identification of a unique target sequence by using a labeled probe; the latter are classified as nucleic acid amplification tests.

nucleic acid test

(noo-klē′ik, nū-),

NAT

A test for the presence of specific genetic material in a laboratory specimen, e.g., a specific segment of viral DNA or RNA in a blood sample. NATs are used, e.g., to detect contamination of blood by hepatitis viruses and HIV during the initial period of infection, before viral antigens appear in the blood of infected patients.
References in periodicals archive ?
According to Medigen, China has been trying vigorously to upgrade the blood-usage safety in recent years, creating a strong demand for nucleic acid test agents.
Gen-Probe is a global leader in the development, manufacture and marketing of rapid, accurate and cost-effective nucleic acid tests (NATs) that are used primarily to diagnose human diseases and screen donated human blood.
Of the 97 HIV-2 cases with positive HIV-1 immunoblot results, the diagnosis of HIV-2 was established by a type-differentiating antibody immunoassay in 46 cases, by an HIV-2 nucleic acid test in 22 cases, and by both in 29 cases (Table 1).
13 October 2014 - US molecular diagnostics maker Nanosphere Inc (NASDAQ:NSPH) said Monday the US FDA had granted 510(k) approval to its Verigene Enteric Pathogens (EP) nucleic acid test, which now includes additional viral targets.
San Diego, CA, has received FDA approval for its amplified nucleic acid test to be used by blood banks to simultaneously detect human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV).
8 September 2014 - US molecular diagnostics system developer Nanosphere Inc (NASDAQ:NSPH) reported Monday positive findings from three outcomes trials showing the clinical and economic impact of its Verigene Gram-Positive Blood Culture Nucleic Acid Test (BC-GP) for rapid sepsis diagnostic testing.
47 million in supplemental contract funding from the National Heart, Lung, and Blood Institute of the US National Institutes of Health (NIH) to continue development of its nucleic acid test (NAT) for the detection of West Nile virus (WNV) in donated blood and organs.
14 July 2014 - US provider of point-of-care (POC) diagnostics and services Alere Inc (NYSE:ALR) unveiled today study findings showing that its Alere q HIV-1/2 Detect assay, the prototype of the company's new POC nucleic acid test, had accurately and rapidly detected HIV in infants in Mozambique.
have developed a combination human immunodeficiency virus/hepatitis C virus nucleic acid test that is currently used to screen more than 70% of United States blood donations under an investigational new drug application.
M2 PHARMA-June 25, 2014-FDA approves bacterial portion of Nanosphere's Verigene Enteric Pathogens nucleic acid test
Schumacher, Founder, CEO, and chairman of Boston Biomedica said: "Molecular diagnostics is one of the fastest growing sectors of laboratory medicine today, and reflects the rapid application of nucleic acid test methods to research, pharmaceuticals and genetics.
Contract awarded for Supply and Delivery of Nucleic Acid Test (NAT) Tube