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novobiocin |
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novobiocin [no″vo-bi´o-sin] an antibacterial produced by Streptomyces niveus, used in the treatment of infections caused by staphylococci and other gram-positive organisms. It should be kept in reserve to be used only when necessary, that is, when resistance to other agents has developed. It is effective against infections caused by penicillin-resistant microorganisms, but organisms have been able to develop resistance to novobiocin rapidly. Leukopenia in some patients and jaundice in infants have been observed after novobiocin administration.
novobiocin an antibacterial produced by Streptomyces niveus, used in the treatment of infections caused by staphylococci and other gram-positive organisms. Called also albamycin, cathomycin. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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It includes the company' s inhibitor-free Buffered Peptone Water, which supports the recovery of sublethally damaged organisms prior to further enrichment in media such as Rappaport Vassiliadis Broth, Mueller Kaufmann Tetrathionate Novobiocin Broth (MKTTn) and Selenite Broth. coli and Listeria) was formulated by scientists who compared its performance with other common selective media--modified EC broth with novobiocin for E coli O157:H7, Fraser broth for Listeria, and Rappaport-Vassiliadis broth for Salmonella. Standard antibiotics of chloramphenicol 30 [micro]g, streptomycin 10 [micro]g, tetracycline 30 [micro]g, erythromycin 15 [micro]g, neomycin 30 [micro]g, novobiocin 30 [micro]g, kanamycin 30 [micro]g, and penicillium G 10 units were used as positive controls. |
novobiocin |
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