norfloxacin


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Related to norfloxacin: ofloxacin, ciprofloxacin

norfloxacin

 [nor-flok´sah-sin]
a broad-spectrum quinolone antibacterial agent effective against penicillin-resistant gram-negative and gram-positive bacteria.

norfloxacin

/nor·flox·a·cin/ (nor-flok´sah-sin) a broad-spectrum antibacterial effective against a wide range of aerobic gram-negative and gram-positive organisms.

norfloxacin

(nôr-flŏk′sə-sĭn)
n.
An oral antibiotic, C20H24N5O4, of the fluoroquinolone class.

norfloxacin

[nôrflok′səsin]
an oral antibacterial drug.
indications It is prescribed for the treatment of bacterial urinary tract infections, sexually transmitted gonorrhea, and proctitis.
contraindications Hypersensitivity to quinolones or pregnancy or lactation prohibits its use. It should be used with caution in patients younger than 18 years because of arthropathy. Concomitant use of nitrofurantoin drugs is not recommended, and concomitant use of corticosteroids can increase the risk of arthropathy in the elderly.
adverse effects Typical side effects include nausea, dizziness, and headache. Severe hypersensitivity reactions, tendon rupture, and numerous other effects have been reported with relatively low incidence.

norfloxacin

Antibiotics A broad-spectrum–gram-negative bacilli, staphylococci–fluoroquinolone with limited activity against streptococci and anaerobes. See Fluoroquinolone.

norfloxacin

A quinolone antibacterial drug used to treat urinary tract infections. A brand name is Utinor.

antibiotic 

1. Pertaining to the ability to destroy or inhibit other living organisms.
2. A substance derived from a mould or bacterium, or produced synthetically, that destroys (bactericidal) or inhibits the growth (bacteriostatic) of other microorganisms and is thus used to treat infections. Some substances have a narrow spectrum of activity whereas others act against a wide range of both gram-positive and gram-negative organisms (broad-spectrum antibiotics). Antibiotics can be classified into several groups according to their mode of action on or within bacteria: (1) Drugs inhibiting bacterial cell wall synthesis, such as bacitracin, vancomycin and the β-lactams based agents (e.g. penicillin, cephalosporins (e.g. ceftazidime, ceftriaxone, cefuroxime). (2) Drugs affecting the bacterial cytoplasmic membrane, such as polymyxin B sulfate and gramicidin. (3) Drugs inhibiting bacterial protein synthesis, such as aminoglycosides (e.g. amikacin sulfate, framycetin sulfate, gentamicin, neomycin sulfate and tobramycin), tetracyclines, macrolides (e.g. erythromycin and azithromycin) and chloramphenicol. (4) Drugs inhibiting the intermediate metabolism of bacteria, such as sulfonamides (e.g. sulfacetamide sodium) and trimethoprim. (5) Drugs inhibiting bacterial DNA synthesis, such as nalixidic acid and fluoroquinolones (e.g. ciprofloxacin, levofloxacin, moxifloxacin, norfloxacin and ofloxacin). (6) Other antibiotics such as fusidic acid, the diamidines, such as propamidine isethionate and dibrompropamidine. Syn. antibacterial. See antiinflammatory drug; fusidic acid.

norfloxacin (nôrflok´səsēn),

n brand name: Noroxin;
drug class: fluoroquinolone antiinfective;
action: a broad-spectrum bactericidal agent that inhibits the enzyme DNA gyrase needed for replication of DNA;
uses: adult urinary tract infections.

norfloxacin

a fluoroquinolone antibiotic, used particularly in urinary tract infection.
References in periodicals archive ?
The uropathogens were more resistant to Nalidixic acid, Norfloxacin and fluoroquinolones and many are found to be multi-drug resistant isolates.
less than or 6-15 >15 equal to]5 Ampicillin 57 8 28 Trimothprim/ sulfamethoxazole 94 16 50 Nalidixic acid 98 17 46 Norfloxacin 64 11 30 Cefotaxime 5 0 5 Cefixime 9 0 8 [less than or 6-15 >15 equal to]5 Ampicillin 50 8 23 Trimothprim/ sulfamethoxazole 93 0 41 Nalidixic acid 88 18 40 Norfloxacin 16 4 10 Cefotaxime 10 3 3 Cefixime 8 2 3 Note: Table made from bar graph.
8] CFU/ml) into each tube containing 5 ml fresh broth with norfloxacin at 1/2 MIC concentration alone as well as in combination with CD.
All the three most frequently isolated organisms showed resistant to commonly used antibiotics like Ampicillin, Norfloxacin and Nalidixic acid.
Besides the enhancement of the light mediated toxic activity of the extracts, these activities were lower than that observed by the norfloxacin and 8-MOP (Table II).
9 (n = 3) percent isolates showed resistance to amoxicillin, oxytetracycline, norfloxacin, enrofloxacin and ciprofloxacin, respectively.
The antibiotics used were penicillin, ampicillin, oxacillin, erythromycin, polymyxin B sulphate, tetracycline, chloramphenicol, vancomycin, rifampin and norfloxacin.
They also assess technologies for human infant health, including molecular imaging, metabolic profiling, and screening of newborns for metabolic disorders, while papers on the health challenges of human infants include considerations of obesity, intestinal immune health, gut decontamination through norfloxacin and insulin, individual epigenetic variation, the relationship of early infant feeding and heredity and the development of allergies and sensitivity, and personalized care of pediatric cancer patients.
with Streptomycin (10 [micro]g), Erythromycin (15 [micro]g), Tetracycline (30 [micro]g), Penicillin (10 [micro]g), Norfloxacin (10 [micro]g), Riphampicin (5 [micro]g), Neomycin (30 [micro]g), Cephalexin (30 [micro]g), Ampicillin (10 [micro]g), Kanamycin (20 [micro]g), Gentamicin (10 [micro]g) were used.
Medications on the list include the fluoroquinolones ciprofloxacin (Cipro), levofloxacin (Levaquin), moxifloxacin (Aveiox), norfloxacin (Noroxin), and ofloxacin (Floxin).
The antimicrobial susceptibility tests included the following drugs: amikacin (an aminoglycoside), cephalexin, cefuroxime and cephotaxime (1st, 2nd and 3rd generation cephalosporins, respectively), norfloxacin, ciprofloxacin and nalidixic acid (fluoroquinolines), nitrofurantoin, ampicillin, and trimethoprim-sulfamethoxazole (TMP/SMX).