norethindrone /nor·eth·in·drone/ (nor-eth´in-drōn) a progestational agent having some anabolic, estrogenic, and androgenic properties; used as the base or the acetate ester in the treatment of amenorrhea, dysfunctional uterine bleeding, and endometriosis, and as an oral contraceptive.
norethindrone
nor·eth·in·drone (nôr- th  n-dr n )n. A progestational agent with some estrogenic and androgenic activity that is used as a substitute for progesterone and, in combination with an estrogen, as an oral contraceptive. |
norethindrone
[nôreth′indrōn]
a progestin.
indications It is prescribed in the treatment of abnormal uterine bleeding and endometriosis and is used alone or as a component in oral contraceptive medications.
contraindications Thrombophlebitis, liver dysfunction, unusual vaginal bleeding, breast cancer, or known hypersensitivity to this drug prohibits its use. It is not recommended for use during pregnancy and should be used with caution in patients with asthma, diabetes, cardiac or renal dysfunction, hyperlipidemia, migraines, seizure disorders, or psychic depression.
adverse effects Among the more serious adverse effects are breakthrough bleeding, amenorrhea, GI disturbances, breast changes, and masculinization of the female fetus. The drug should be discontinued immediately if vision problems (e.g., double vision, complete or partial loss of vision) or migraine headaches appear. Progestin-only contraceptives have a higher rate of failure.
norethisterone, norethindrone
a progestin.
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