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noradrenergic

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
noradrenergic /nor·ad·ren·er·gic/ (-ah-dren-urj´ik) activated by or secreting norepinephrine.
nor·ad·ren·er·gic (nôrd-r-nûrjk)
adj.
Stimulated by or releasing norepinephrine.

noradrenergic [nor″ah-dren-er´jik]
activated by or secreting norepinephrine.

noradrenergic
activated by or secreting norepinephrine.


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The rationale behind the development of fipamezole is to increase noradrenergic release in certain areas of the brain, resulting in rebalancing of the distorted brain network and potentially alleviating symptoms of advanced Parkinson's disease such as dyskinesia, motor fluctuations, orthostatic hypotension and cognitive impairment without exacerbating the underlying Parkinsonian features of the disease.
Chapter topics include: the role of prefrontal cholinergic receptors in the pathology of schizophrenia; participation of the prefrontal cortex in the processing of sexual and maternal incentives; the orbitofrontal cortex and emotional decision-making; the role of the prefrontal cortex in cognitive impairment in Parkison's disease, and noradrenergic actions in prefrontal cortex as they relate to AD/HD.
Some LC noradrenergic neurons project to brainstem and spinal motor neurons.
 
 
 
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