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nonsteroidal antiinflammatory drug |
Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson | 0.06 sec. |
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drug (drug) 1. a chemical substance that affects the processes of the mind or body. 2. any chemical compound used in the diagnosis, treatment, or prevention of disease or other abnormal condition. 3. a substance used recreationally for its effects on the central nervous system, such as a narcotic. 4. to administer a drug to. designer drug a new drug of abuse similar in action to an older abused drug and usually created by making a small chemical modification in the older one. mind-altering drug one that produces an altered state of consciousness. nonsteroidal antiinflammatory drug (NSAID) any of a large, chemically heterogeneous group of drugs that inhibit the enzyme cyclooxygenase, resulting in decreased synthesis of prostaglandin and thromboxane precursors; they have analgesic, antipyretic, and antiinflammatory actions. orphan drug one that has limited commercial appeal because of the rarity of the condition it is used to treat. psychoactive drug , psychotropic drug see under substance. nonsteroidal antiinflammatory drug (NSAID) [-stir′oidəl] any of a group of drugs having antipyretic, analgesic, and antiinflammatory effects. They counteract or reduce inflammation by inhibiting cyclooxygenase, the enzyme responsible for prostaglandin synthesis. NSAIDs may be indicated in the treatment of mild-to-moderate pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylosis, gouty arthritis, fever, nonrheumatic inflammation, and dysmenorrhea. Classic examples include aspirin, ibuprofen, and ketoprofen. Newer drugs such as celecoxib, refecoxib, and valdecoxib selectively block only the inductible form of cyclooxygenase (COX-2), the form of the enzyme that appears in cells at sites of inflammation, and tend to have fewer side effects. Patient discussion about nonsteroidal antiinflammatory drug. Q. Is there any good source for heel pain relief, besides NSAIDs? My heel pain is most severe at night when I sleep. It's as if the way I position my feet worsen the condition, but I'm at a loss to know how to position my feet. During the day my heels feel so but don't typically bother me. A. I have found that keeping my feet flexed (the position they are in when standing) helps ease the pain of plantar facitis. I also don't let my feet get cold(wear socks)and keep heavy blankets and quilts off the feet. Placing a box under the covers at the foot of the bed will help keep the blankets up. Do try the exercises recommended on the above web sites. It usually resolves in about 6 months. Best wishes! Read more or ask a question about nonsteroidal antiinflammatory drugHow to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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