For conventional transplantation, such as bone marrow transplantation, myeloablative allogeneic stem cell transplantation and nonmyeloablative
allogeneic stem cell transplantation, GVHD after transplantation cannot be avoided.
This patient received a nonmyeloablative
transplant and had bone marrow chimerism of 99.
Slavin's groundbreaking work in oncological cell therapy by post allogeneic stem cell transplantation, donor lymphocyte infusions (DLI) and nonmyeloablative
stem cell transplantation (NST) is in use worldwide.
Thus, thrombopoietins are active in diseases with BM megakaryocyte mass such as ITP and thrombocytopenia following nonmyeloablative
hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus.
Two patients received donor cell infusion after failure of nonmyeloablative
Transfusion-associated babesiosis with an atypical time course after nonmyeloablative
transplantation for sickle cell disease.
His surgical history included thyroidectomy, nonmyeloablative
allogeneic stem cell transplant, and transjugularintrahepaticportosystemic shunt (TIPS) placement.
A previous study found that autologous nonmyeloablative
hematopoietic stem cell transplantation (HSCT) in 15 patients with newly diagnosed type 1 DM resulted in the majority of patients becoming insulin free during the follow-up, which averaged about 19 months.
While we do perform standard transplants, our progress in BMT has afforded us the opportunity to transplant rarer and higher-risk disease and explore new transplant options, such as nonmyeloablative
transplant," Parran explains.
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative
More recently, lower-dose, nonmyeloablative
conditioning regimens have shown promise.