splenomegaly

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splenomegaly

 [sple″no-meg´ah-le]
enlargement of the spleen.
congestive splenomegaly splenomegaly secondary to portal hypertension, with ascites, anemia, thrombocytopenia, leukopenia, and episodic hemorrhage from the intestinal tract. Called also Banti's disease.
hemolytic splenomegaly enlargement of the spleen associated with hemolytic diseases of the blood.
siderotic splenomegaly splenomegaly with deposit of iron and calcium.

sple·no·meg·a·ly

, splenomegalia (splē'nō-meg'ă-lē, -mĕ-gā'lē-ă),
Enlargement of the spleen.
Synonym(s): megalosplenia
[spleno- + G. megas (megal-), large]

splenomegaly

/sple·no·meg·a·ly/ (-meg´ah-le) enlargement of the spleen.
congestive splenomegaly  Banti's disease; splenomegaly secondary to portal hypertension.
hemolytic splenomegaly  that associated with any disorder causing increased erythrocyte degradation.

splenomegaly

(splē′nō-mĕg′ə-lē, splĕn′ō-)
n. pl. splenomega·lies
Enlargement of the spleen.

splenomegaly

[splē′nōmeg′əlē, splen′-]
Etymology: Gk, splen + megas, large
an abnormal enlargement of the spleen, as is associated with portal hypertension, hemolytic anemia, Niemann-Pick disease, or malaria.
enlarge picture
Splenomegaly

splenomegaly

Enlarged spleen Enlargement of spleen for any reason, which is usually a manifestation of underlying disease; the only specific finding in splenomegaly is dragging sensation in the upper right quadrant; megalic spleens may reach 4.0+ kg–eg, in agnogenic myeloid metaplasia
Splenomegaly
Congestion Cirrhosis, CHF, thrombosis of portal or splenic veins
Infection
• Bacteria Brucellosis, infective carditis agents, syphilis, TB, typhoid fever
• Fungi Histoplasmosis
• Parasites Echinococcosis, leishmaniasis, malaria, schistosomiasis, toxoplasmosis, trypanosomiasis
• Viruses CMV, EBV
Inflammatory/immune-related Rheumatoid arthritis, SLE
Hematopoietic disease/Lymphoid function
• Malignant Leukemias, eg ALL, CLL, myeloproliferative disorders–eg agnogenic myeloid metaplasia, CML, multiple myeloma, polycythemia vera; lymphomas–Hodgkin's disease, NHL
• Nonmalignant Hemolytic anemia, histiocytosis, ITP
Storage diseases Gaucher's disease, mucopolysaccharidosis, Niemann-Pick disease
Etc Amyloidosis, cysts, hypersplenism, metastases, primary tumors

sple·no·meg·a·ly

, splenomegalia (splēnō-megă-lē, -mĕ-gālē-ă)
Enlargement of the spleen.
Synonym(s): megalosplenia.
[spleno- + G. megas (megal-), large]

splenomegaly

SPLEEN ENLARGEMENT.

Splenomegaly

Abnormal enlargement of the spleen. Splenomegaly is a major diagnostic criterion of PV.

splenomegaly (spleˈ·nō·meˑ·g·lē),

n an abnormal increase in the size of the spleen; often associated with hemolytic anemia, mononucleosis, leukemia, portal hypertension, or malaria.
Enlarge picture
Splenomegaly.

sple·no·meg·a·ly

, splenomegalia (splēnō-megă-lē, -mĕ-gālē-ă)
Enlargement of the spleen.
[spleno- + G. megas (megal-), large]

splenomegaly (splē´nōmeg´əlē),

n an abnormal enlargement of the spleen, usually associated with portal hypertension, hemolytic anemia, and malaria.

splenomegaly

enlargement of the spleen. Is largely without clinical signs but it may be palpated during an examination through the abdominal wall in dogs and cats, rectally in horses and not at all in ruminants. The enlargements may be caused by abscess or neoplasm or there may be a diffuse enlargement caused by accumulation of hemolyzed red cells.

asymmetrical splenomegaly
usually the result of trauma or neoplasia.
congestive splenomegaly
in animals, most often caused by splenic torsion.
hemolytic splenomegaly
that associated with hemolytic anemia.
siderotic splenomegaly
splenomegaly with deposit of iron and calcium.
symmetrical splenomegaly
usually caused by congestion or infiltration of the splenic tissue.
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