splenomegaly

(redirected from nonmalignant)
Also found in: Dictionary, Thesaurus, Legal, Encyclopedia.
Related to nonmalignant: benign

splenomegaly

 [sple″no-meg´ah-le]
enlargement of the spleen.
congestive splenomegaly splenomegaly secondary to portal hypertension, with ascites, anemia, thrombocytopenia, leukopenia, and episodic hemorrhage from the intestinal tract. Called also Banti's disease.
hemolytic splenomegaly enlargement of the spleen associated with hemolytic diseases of the blood.
siderotic splenomegaly splenomegaly with deposit of iron and calcium.

sple·no·meg·a·ly

, splenomegalia (splē'nō-meg'ă-lē, -mĕ-gā'lē-ă),
Enlargement of the spleen.
Synonym(s): megalosplenia
[spleno- + G. megas (megal-), large]

splenomegaly

/sple·no·meg·a·ly/ (-meg´ah-le) enlargement of the spleen.
congestive splenomegaly  Banti's disease; splenomegaly secondary to portal hypertension.
hemolytic splenomegaly  that associated with any disorder causing increased erythrocyte degradation.

splenomegaly

(splē′nō-mĕg′ə-lē, splĕn′ō-)
n. pl. splenomega·lies
Enlargement of the spleen.

splenomegaly

[splē′nōmeg′əlē, splen′-]
Etymology: Gk, splen + megas, large
an abnormal enlargement of the spleen, as is associated with portal hypertension, hemolytic anemia, Niemann-Pick disease, or malaria.
enlarge picture
Splenomegaly

splenomegaly

Enlarged spleen Enlargement of spleen for any reason, which is usually a manifestation of underlying disease; the only specific finding in splenomegaly is dragging sensation in the upper right quadrant; megalic spleens may reach 4.0+ kg–eg, in agnogenic myeloid metaplasia
Splenomegaly
Congestion Cirrhosis, CHF, thrombosis of portal or splenic veins
Infection
• Bacteria Brucellosis, infective carditis agents, syphilis, TB, typhoid fever
• Fungi Histoplasmosis
• Parasites Echinococcosis, leishmaniasis, malaria, schistosomiasis, toxoplasmosis, trypanosomiasis
• Viruses CMV, EBV
Inflammatory/immune-related Rheumatoid arthritis, SLE
Hematopoietic disease/Lymphoid function
• Malignant Leukemias, eg ALL, CLL, myeloproliferative disorders–eg agnogenic myeloid metaplasia, CML, multiple myeloma, polycythemia vera; lymphomas–Hodgkin's disease, NHL
• Nonmalignant Hemolytic anemia, histiocytosis, ITP
Storage diseases Gaucher's disease, mucopolysaccharidosis, Niemann-Pick disease
Etc Amyloidosis, cysts, hypersplenism, metastases, primary tumors

sple·no·meg·a·ly

, splenomegalia (splēnō-megă-lē, -mĕ-gālē-ă)
Enlargement of the spleen.
Synonym(s): megalosplenia.
[spleno- + G. megas (megal-), large]

splenomegaly

SPLEEN ENLARGEMENT.

Splenomegaly

Abnormal enlargement of the spleen. Splenomegaly is a major diagnostic criterion of PV.

splenomegaly (spleˈ·nō·meˑ·g·lē),

n an abnormal increase in the size of the spleen; often associated with hemolytic anemia, mononucleosis, leukemia, portal hypertension, or malaria.
Enlarge picture
Splenomegaly.

sple·no·meg·a·ly

, splenomegalia (splēnō-megă-lē, -mĕ-gālē-ă)
Enlargement of the spleen.
[spleno- + G. megas (megal-), large]

splenomegaly (splē´nōmeg´əlē),

n an abnormal enlargement of the spleen, usually associated with portal hypertension, hemolytic anemia, and malaria.

splenomegaly

enlargement of the spleen. Is largely without clinical signs but it may be palpated during an examination through the abdominal wall in dogs and cats, rectally in horses and not at all in ruminants. The enlargements may be caused by abscess or neoplasm or there may be a diffuse enlargement caused by accumulation of hemolyzed red cells.

asymmetrical splenomegaly
usually the result of trauma or neoplasia.
congestive splenomegaly
in animals, most often caused by splenic torsion.
hemolytic splenomegaly
that associated with hemolytic anemia.
siderotic splenomegaly
splenomegaly with deposit of iron and calcium.
symmetrical splenomegaly
usually caused by congestion or infiltration of the splenic tissue.
References in periodicals archive ?
Libby workers experienced significant excess mortality from asbestosis and other nonmalignant respiratory diseases (Table 2).
In spite of these positive developments, we do not expect a significant reduction in total asbestos claim liabilities because we expect the increase in payments made to malignant claimants to largely offset the reductions expected from the nonmalignant claimants.
The purpose of the Phase 3, multicenter, open-label study was to determine the long-term safety, tolerability and efficacy of subcutaneous methylnaltrexone in patients with chronic nonmalignant pain.
Findings showed that malignant effusion exhibited elevated IL-17 levels compared with nonmalignant effusion (20.
The authors' original set included 44 malignant lesions and 6 nonmalignant lesions (see their Table 1).
Still, many pain physicians have stopped prescribing opioids for chronic nonmalignant pain--partly out of disappointment that the use of opioids hasn't resulted in the end of pain.
Patients and controls, seen at hospitals in four regions throughout Italy, had completed a questionnaire and had provided a self-report on their medical history for several nonmalignant conditions, including high cholesterol level and gallstones (Ann.
Expression of RLIP76 was found to be greater in malignant cells than in nonmalignant cells.
With varying degrees of severity, the laws seek to rein in nonmalignant claims by boosting medical criteria and venue rules and were pushed by defendant corporations and insurers as Congressional efforts at reform have been slow in coming
We average 10 narcotic renewals a day for patients with chronic nonmalignant pain.
Unless you can get the gene [that enables unrestricted cell growth] out of absolutely every cell," warns Furlanetto, "there's a possibility of developing insulinoma," a nonmalignant islet tumor that can cause dangerously low blood sugar.
Doctors at the West Los Angeles VA Medical Center and UCLA said they believe the virus, called Kaposi's sarcoma-associated herpes virus, or KSHV, might trigger malignant tumors in bone marrow by infecting nonmalignant cells.