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nonadrenergic noncholinergic

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nonadrenergic noncholinergic (NANC) neuron (nnˈ·a·dr·nurˑ·jik nnˑ·kō·li·nurˑ·jik),
n an autonomic, efferent nerve cell, the method of transmission of which is not based upon adrenergic (e.g., epinephrine, dopamine) or cholinergic (i.e., acetylcholine) neurotransmitters.


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8,9,11,16) Although the abnormalities of enteric nerves, including adrenergic, cholinergic, nonadrenergic noncholinergic (peptidergic), and nitrergic nerves, have been suggested to be the cause of bowel dysfunction in this condition, the exact pathogenesis of HD is not fully understood.
This system exerts both proerectile and antierectile actions at the central and peripheral levels through adrenergic, cholinergic, and nonadrenergic noncholinergic (NANC) neurotransmitters (Burnett, 1999; Giuliano et al.
Since the dense reticular network of ICCs intimately surrounds the nitrergic neuronal plexus and demonstrates abundant gap junctions connected with smooth muscle cells and nerve fibers, it is very likely that these cells play a role as a mediator in neurotransmission, possibly the nonadrenergic noncholinergic inhibition.
 
 
 
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