non-ulcer dyspepsia

non-ulcer dyspepsia

GI disease A condition characterized by ulcer Sx in absence of ulceration; 30-60% of dyspeptics have no demonstrable gross lesions Clinical Sx range from a classic duodenal ulcer–epigastric burning 1-3 hrs after meals, relieved by food or alkali to functional indigestion–bloating, belching, fullness, and nausea, not relieved by antacids and worsened by meals; fat intolerance is common Endoscopy The duodenal mucosa demonstrates edema, erythema, petechial hemorrhage, erosions. See GERD. Cf Dumping syndrome.