hepatitis /hep·a·ti·tis/ (hep″ah-ti´tis) pl. hepati´tides Inflammation of the liver.
non-A, non-B hepatitis
hepatitis A a self-limited viral disease of worldwide distribution, usually transmitted by oral ingestion of infected material but sometimes transmitted parenterally; most cases are clinically inapparent or have mild flu-like symptoms; any jaundice is mild.
anicteric hepatitis viral hepatitis without jaundice.
hepatitis B an acute viral disease transmitted primarily parenterally, but also orally, by intimate personal contact, and from mother to neonate. Prodromal symptoms of fever, malaise, anorexia, nausea, and vomiting decline with the onset of clinical jaundice, angioedema, urticarial skin lesions, and arthritis. After 3 to 4 months most patients recover completely, but some may become carriers or remain ill chronically.
hepatitis C a viral disease caused by the hepatitis C virus, commonly occurring after transfusion or parenteral drug abuse; it frequently progresses to a chronic form that is usually asymptomatic but that may involve cirrhosis.
cholangiolitic hepatitis cholestatic h. (1).
cholestatic hepatitis
1. inflammation of the bile ducts of the liver associated with obstructive jaundice.
2. hepatic inflammation and cholestasis resulting from reaction to drugs such as estrogens or chlorpromazines.
hepatitis D , delta hepatitis infection with hepatitis D virus, occurring either simultaneously with or as a superinfection in hepatitis B, whose severity it may increase.
hepatitis E a type transmitted by the oral-fecal route, usually via contaminated water; chronic infection does not occur but acute infection may be fatal in pregnant women.
enterically transmitted non-A, non-B hepatitis (ET-NANB) h. E.
hepatitis G a post-transfusion disease caused by hepatitis G virus, ranging from asymptomatic infection to fulminant hepatitis.
infectious hepatitis h. A.
infectious necrotic hepatitis black disease.
lupoid hepatitis chronic active hepatitis with autoimmune manifestations.
neonatal hepatitis hepatitis of uncertain etiology occurring soon after birth and marked by prolonged persistent jaundice that may progress to cirrhosis.
non-A, non-B hepatitis a syndrome of acute viral hepatitis occurring without the serologic markers of hepatitis A or B, including hepatitis C and hepatitis E.
posttransfusion hepatitis viral hepatitis, now primarily hepatitis C, transmitted via transfusion of blood or blood products, especially multiple pooled donor products such as clotting factor concentrates.
serum hepatitis h. B.
transfusion hepatitis posttransfusion h.
non-A, non-B hepatitis (n n-  nn-b )n. Abbr. NANB hepatitis Hepatitis that is caused by a virus that is antigenically different from hepatitis viruses A and B. |
non-A, non-B hepatitis
A group of hepatitides which are the major cause of transfusion-related hepatitis Incidence 7/105/yr–US Risk factors 42% IV drug abuse, 40% unknown risk factors, 6% sexual contact, 6% blood transfusion, 3%
household contact, 2% health care professional; of the ±150,000 new cases/yr–US, 30-50% become chronic carriers–20% of these develop cirrhosis; NANBH may also be enteric–parenteral; NANBH is most commonly due to HCV and
enteric NANBH to HEV Management IFN-α2b results in significant histologic reversal and serum ALA response Prognosis No ↑ in overall mortality with chronic NANBH, but ↑ liver-related deaths. See Hepatitis.
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