NOG

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NOG

A gene on chromosome 17q22 that encodes noggin, a protein that inhibits TGF-beta signal transduction by binding to TGF-beta family ligands, preventing them from binding to their cognate receptors. Noggin plays a key role in neural induction by inhibiting BMP4 and other TGF-beta signalling inhibitors (e.g., chordin and follistatin), and it is required for cartilage morphogenesis and joint formation.
References in periodicals archive ?
Structural basis of BMP signaling inhibition by the cystine knot protein Noggin.
The existence of noggin and connection between 2 studs causes 2-percent strength increase in comparing with the same frame without noggin.
RT-PCR on somite-derived cells revealed identifiable expression of cerberus, chordin, FGF8, follistatin and noggin after 7 days (Figure 1).
With the permission of customers, the bank took their photos in front of a poster containing Noggin "thought bubbles.
After showing a refurbished episode of Noggin the Nog at the National Film Theatre in 1999, Postgate was so pleased he handed Loaf the rights.
As Life Noggin explains, even though it's time consuming and illogical, people who suffer with the disorder can't stop themselves.
Wearing the aircrew integrated helmet system (AIHS) can be uncomfortable if you just jam it on your noggin.
Oliver Postgate also counted Noggin The Nog, Ivor The Engine, Pingwings and The Pogles - which have delighted children since the 1950s - among his creations.
His other creations, including Noggin the Nog, Ivor the Engine and Ping-wings, were screened on the BBC and ITV from the 1950s.
Coun Bill Archer, aged 80, has been writing A Noggin of Bread and Jam for three years.
In the last few years, Playhouse Disney, PBS Kids, Sprout, Toon Disney, and other channels have come on line, joining not only Noggin but Nickelodeon and more.
The Noggin SmartCart is an integrated GPR system used to locate subsurface utilities prior to construction or excavation.