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no-reflow phenomenon

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.07 sec.
phenomenon /phe·nom·e·non/ (fĕ-nom´ĕ-non) pl. phenom´ena   any sign or objective symptom; an observable occurrence or fact.
booster phenomenon  on a tuberculin test, an initial false-negative result due to a diminished amnestic response, becoming positive on subsequent testing.
dawn phenomenon  the early morning increase in plasma glucose concentration and thus insulin requirement in patients with type 1 diabetes mellitus.
Koebner's phenomenon  a cutaneous response seen in certain dermatoses, manifested by the appearance on uninvolved skin of lesions typical of the skin disease at the site of trauma, on scars, or at points where articles of clothing produce pressure.
Marcus Gunn's pupillary phenomenon  with unilateral optic nerve or retinal disease, a difference between the pupillary reflexes of the two eyes; on the affected side there is abnormally slight contraction or even dilatation of the pupil when a light is shone in the eye.
no-reflow phenomenon  when cerebral blood flow is restored following prolonged global cerebral ischemia, there is initial hyperemia followed by a gradual decline in perfusion until there is almost no blood flow.
Somogyi phenomenon  a rebound phenomenon occurring in diabetes: overtreatment with insulin induces hypoglycemia, thus initiating hormone release; this stimulates lipolysis, gluconeogenesis, and glycogenolysis, which in turn cause rebound hyperglycemia and ketosis.

no-reflow phenomenon
a failure of reperfusion to occur after adequate fluid therapy for shock due to microvascular injury.

no-reflow phenomenon
Cardiology The finding that restoration of antegrade flow in an occluded epicardial artery in acute MI may not result in recovery of microvascular tissue perfusion; Pts with NRP have lower
1-month ejection fractions, larger end-diastolic volumes, and more persistent heart failure; Pts at high risk with significant zones of no reflow after thrombolytics might need emergency coronary angiography, and benefit from early and aggressive ACE inhibition to prevent LV remodeling. See Ventricular remodeling.


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