The dopaminergic nigrostriatal
pathway has been linked to the symptoms of PD (Bergman & Deuschl, 2002) because this pathway connects the substantia nigra (the source of dopaminergic neurons) with other parts of the basal ganglia and brain, facilitating coordinated movement.
Age-specific progression of nigrostriatal
dysfunction in Parkinson's disease.
Reference: "Non-exercise physical activity attenuates motor symptoms in Parkinson disease independent from nigrostriatal
degeneration," Parkinsonism and Related Disorders(2015).
20) suggests that impaired information process in ADHD impairs adaptation to academic norms and this causes anxiety in the executive function disorder model of Barkley (2'), the author has reported that impairment in executive functions impairs the social behaviors and the relationships with family and friends and this may cause anxiety Levy (19) has suggested that impairment in mesolimbic, mesocortical, and nigrostriatal
cycles because of impairment in the physiology of nucleus accumbency in ADHD causes anxiety Approaching to this situation through a different angle, ADHD-like symptoms such as hyperactivity and inattentiveness may also be observed in AD (22).
pathway of dopamine (in the subcortical areas of the brain) has a prominent role in motor planning and movement, plus cognition.
Action of |3-phenylethylamine and related amines on nigrostriatal
Results showed that after follow-up, patients' SPECT scans revealed substantial decreases in radiotracer binding to the dopamine transport system in the nigrostriatal
regions of the brain.
Protection of dichlorvos induced oxidative stress and nigrostriatal
neuronal death by chronic coenzyme Q10 pretreatment.
It is known that stimulation of 5HT2A receptors reduces dopamine release in the mesolimbic, nigrostriatal
, and mesocortical pathways (Stahl 2008).
Parkinson's disease (PD) is a progressive neurodegenerative disorder secondary to the loss of dopaminergic neurons in the nigrostriatal
pathway: Dysfunction in the nigrostriatal
pathway, part of the basal ganglia, is associated with Parkinson's disease.
2006, 'Cognitive function and nigrostriatal
markers in abstinent methamphetamine abusers', Psychopharmacology 185, 327-338.