nicotinamide adenine dinucleotide


Also found in: Dictionary, Thesaurus, Financial, Acronyms, Encyclopedia, Wikipedia.
Related to nicotinamide adenine dinucleotide: nicotinamide adenine dinucleotide phosphate, adenosine triphosphate

nic·o·tin·a·mide ad·e·nine di·nu·cle·o·tide (NAD, NAD+, NADH),

(nik'ō-tin'ă-mīd ad'ĕ-nīn dī-nū'klē-ō-tīd),
Ribosylnicotinamide 5'-phosphate (NMN) and adenosine 5'-phosphate (AMP) linked by phosphoanhydride linkage between the two phosphoric groups; binds as a coenzyme to proteins, serves in respiratory metabolism (hydrogen acceptor and donor) through alternate oxidation and reduction (NAD+ ⇋ NADH). See also entries under NAD+ and NADP+

nicotinamide adenine dinucleotide

(nĭk′ə-tĭn′ə-mīd′, -tē′nə-)
n.
NAD.

nic·o·tin·a·mide ad·e·nine di·nu·cle·o·tide

(NAD) (nik'ō-tin'ă-mīd ad'ĕ-nēn dī-nū'klē-ō-tīd)
Ribosylnicotinamide 5'-phosphate (NMN) and adenosine 5'-phosphate (AMP) linked by the two phosphoric groups; binds as a coenzyme to proteins, serves in respiratory metabolism (hydrogen acceptor and donor).
See also: entries under NAD and NADP
Synonym(s): diphosphopyridine nucleotide.

nicotinamide adenine dinucleotide,

n See NADH.
References in periodicals archive ?
Alcohol induces hypoglycemia by inhibiting gluconeogenesis[14,15] as it depletes hepatic nicotinamide adenine dinucleotide (NAD), a cofactor that is necessary for the entry of most precursors into the gluconeogenic pathway.
In this publication, the authors describe how, by using an untargeted metabolomic approach based on Metabolon's proprietary platform, the mode of action of GMX1778 was clearly identified to be in the inhibition of nicotinamide adenine dinucleotide (NAD+) biosynthetic pathway.
The organization launched fall of 2017 with the help of volunteers, who have eagerly collected published research on the health benefits of intravenous nicotinamide adenine dinucleotide (NAD+) therapy.
It reduces oxidant damage to red blood cells by improving the redox potential of nicotinamide adenine dinucleotide, a coenzyme that has been identified as the primary regulator of oxidation.
Endari reduces oxidant damage to red blood cells by improving the redox potential of nicotinamide adenine dinucleotide, a coenzyme that has been identified as the primary regulator of oxidation.
Nicotinamide is a form of vitamin B3 and the precursor of nicotinamide adenine dinucleotide (NAD), a cofactor for ATP production.
Nicotinamide adenine dinucleotide (NAD[sup]+), cADPR, CD38, and intracellular Ca[sup]2+ levels in the lung tissues were measured at 6, 12, 24, and 48 h after CLP surgery.
1 In CGD, the primary defect is associated with the key enzyme, nicotinamide adenine dinucleotide phosphate (NADPH) oxidase.
Glucose-6-phosphate dehydrogenase enzyme maintains a continuous supply of reduced nicotinamide adenine dinucleotide phosphate (NADPH) which in turn is essential for regeneration of reduced glutathione from oxidized glutathione (Gahlawat et al.
The researchers said that the mechanism by which chronic alcohol intake is thought to alter the control of fat metabolism in the liver is also a shared signal to the circadian clock mechanism, this being the ratio of production of reduced nicotinamide adenine dinucleotide, and may be a key to the shared disturbance to the two biological mechanisms of lipid metabolism and the circadian clock.
One such sensor, the protein encoded by the silent information regulator2 (S1R2) gene in yeast (and its mammalian orthologue S1RT1), mediates transcriptional silencing through its nicotinamide adenine dinucleotide (NAD)-dependent histone deacetylase (HDAC) activity.
This reaction is coupled to a second reaction, which uses lactate dehydrogenase to convert pyruvate to lactate with nicotinamide adenine dinucleotide (reduced form) (NADH) as a co-factor.

Full browser ?