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niacin |
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niacin /ni·a·cin/ (ni´ah-sin) nicotinic acid; a water-soluble vitamin of the B complex required by the body for the formation of the coenzymes NAD and NADP, important in biochemical oxidations; used to prevent and treat pellagra and to treat hyperlipidemia.
niacin, n See vitamin B3. niacin (vitamin B n brand name: generic niacin (nicotinic acid); drug class: vitamin B3; action: needed for conversion of fats, protein, carbohydrates by oxidation-reduction; acts directly on vascular smooth muscle, causing vasodilation; uses: pellagra, hyperlipidemias, peripheral vascular disease. niacin a water-soluble vitamin of the B complex found in various animal and plant tissues. Essential for normal carbohydrate metabolism. Most natural animal feeds have high enough content to avoid need for supplementation, except for pigs fed a heavy corn diet. Called also nicotinic acid, vitamin PP. See also nicotinamide. niacin nutritional deficiency causes hemorrhagic diarrhea, dermatitis, anemia and a severe stomatitis with ulceration of the mouth and tongue ('black tongue'). In cats, the signs are diarrhea, emaciation and death. Called also pellagra. niacin production a test for differentiating Mycobacteria tuberculosis (positive) and M. avium (negative). |
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