Radiological features in 82 patients with nevoid
basal cell carcinoma (NBCC or Gorlin) syndrome.
The most exciting of all the diseases I have had in practice has been the nevoid
basal cell carcinoma syndrome, a familial (genetic) basis for multiple early onset basal cell cancers, usually very destructive.
In most cases, the histologic differential diagnosis was between Spitz nevus and spitzoid melanoma or between atypical nevus (such as variants of deep penetrating/clonal/inverted type-A nevus, pigmented spindle cell nevus, atypical genital nevus, atypical conjunctival nevus showing cytologic atypia, mitotic activity, limited maturation, or proliferative nodules, among others) and nevoid
melanoma (Table 1).
telenjiectasis in a patient with chronic hepatitis B virus infection.
Key Words: Unilateral nevoid
Humbert P, Laurent R, Faivre B et al: Nevoid
basal cell carcinoma syndrome and acrokeratosis verruciformis.
Bifid rib may be associated with Gorlin-Goltz basal cell nevus syndrome, a rare autosomal dominant condition characterised by multiple nevoid
basal cell carcinomas, jaw cysts and bifid ribs.
Akrokeratozis verrusiformisin, nevoid
bazal hucreli karsinom ve keratoakantom ile de bir arada goruldugune dair olgu bildirileri bulunmaktadir (9,10).
hyperkeratosis of the nipple and areola: treatment of two patients with topical calcipotriol.
Fetal rhabdomyoma is not generally considered part of nevoid
basal cell carcinoma syndrome.
Similarly, melanomas that show nevoid
morphology may display a low Ki67 index.
We describe the imaging findings in a 13-year-old boy with nevoid
basal cell carcinoma syndrome (NBCCS).