nevirapine


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nevirapine

 [nĕ-vir´ah-pēn]
a nonnucleoside human immunodeficiency virus-1 (HIV-1) reverse transcriptase inhibitor that acts by interfering with the ability of the virus to replicate; used in combination with other antiretroviral agents in treatment of HIV-1 infection, administered orally.

nevirapine

/ne·vir·a·pine/ (nĕ-vir´ah-pēn) a nonnucleoside inhibitor of HIV-1reverse transcriptase, used in combination with other antiretroviral agents in the treatment of HIV infection.

nevirapine

(nə-vîr′ə-pēn′, -pĭn)
n.
An antiviral drug, C15H14N4O, that is a non-nucleoside reverse transcriptase inhibitor and is used in combination with other drugs for the treatment of HIV infection.

nevirapine

an antiretroviral nonnucleoside reverse transcriptase inhibitor.
indication It is prescribed in combination for the treatment of human immunodeficiency virus infection.
contraindications It should not be given to patients with an allergy or sensitivity to the medication or to patients taking ketoconazole or oral contraceptives. When used alone, there is rapid and uniform appearance of viral resistance.
adverse effects The side effects most often reported include headache, rash, drug fever, and diarrhea.

nevirapine

Viramune® AIDS An antiretroviral non-nucleoside reverse transcriptase inhibitor, combined with nucleoside RTIs to manage HIV infection Adverse effects Rash. See Nonnucleoside reverse transcriptase inhibitor, TIBO. Cf Antiretroviral agent, Delavirdine.

nevirapine

A non-nucleoside reverse transcription inhibitor drug used in combination with other antiretroviral drugs to treat HIV infections. The drug is on the WHO official list. A brand name is Viramune.
References in periodicals archive ?
On day 3 after admission, he was prescribed 300 mg zidovudine twice daily, 150 mg lamivudine twice daily and 200 mg nevirapine daily.
Policy makers can now make informed decisions regarding the WHO 2010 prevention of mother-to-child transmission (PMTCT) guidelines and the combined use of nevirapine and co-trimoxazole prophylaxis for extended periods of time.
The clinics followed NACO guidelines for PPTCT and administered a single dose of nevirapine to the mother at the time of delivery and one dose to the infant within 72 h after birth.
The NIH, excited about the very encouraging preliminary results, even released the data before its publication in the peer-reviewed literature, reporting an astonishing 48% decrease in HIV transmission with nevirapine compared with the group receiving a short course of the control, AZT, the previous standard approach to the problem of mother-infant transmission.
Severe hepatotoxicity associated with nevirapine use in HIV-infected subjects.
Nevirapine increases High Density Lipoprotein-cholesterol by stimulation of apolipoprotein AI synthesis.
Reductions in blood levels of contraceptive hormones due to interactions with nevirapine or ritonavir can be substantial.
Where no interventions are used, MTC transmission rates are around 40% and a single dose of nevirapine will nearly halve transmission and is commonly the only means of reducing transmission in developing countries.
4%) had received non-NRTIs (59 patients received only efavirenz, 30 received only nevirapine, and 5 received both) and 53 patients (41.
Morbilliform eruptions appear in 19% of patients treated with nevirapine, including 8% who develop Stevens-Johnson syndrome, "a pretty high number," Dr.
SAN FRANCISCO -- Pregnant women given a single dose of nevirapine during pregnancy to prevent vertical transmission of HIV were more likely to fail their own HIV treatment if it was started within 6 months of taking the nevirapine, Shahin Lockman, M.
based in Cork, Ireland and now part of Johnson & Johnson, is a "second generation" NNRTI (non-nucleoside reverse transcriptase inhibitor)--an antiretroviral in the same class as efavirenz (brand name Sustiva, or Stochrin in many countries) or nevirapine (Viramune).