neutrophil recovery

neutrophil recovery

In neutropenic patients, esp. those who have been treated with chemotherapy or bone marrow transplantation, the return of neutrophil counts to higher than 500 cells/mm3.
References in periodicals archive ?
The study also established early clinical proof-of-concept - trends of accelerated neutrophil recovery, improved 100-day survival and low rates of graft-versus-host disease were evident, and durable and preferential reconstitution with ProHema occurred in 10 of 12 evaluable patients.
In patients receiving MPC-expanded cord blood, the median time to neutrophil recovery was 16 days and to platelet recovery 38 days, compared with approximately 30 days and over 90 days, respectively, in published reports of patients transplanted with an unexpanded cord.
Moreover, a linear relationship between the occurrence of oral mucositis, oral and systemic granulocyte counts, and a coincidence of resolution of mucositis with neutrophil recovery has been demonstrated (Kostler et al.
Moreover, cyclosporine used alone was significantly better at improving outcome than its combined use with other drugs, achieving a neutrophil recovery probability of 73% at day 40.
During the quarter, Amgen presented preliminary phase 2 data at the annual meeting of the American Society of Hematology demonstrating that neutrophil recovery following a single injection of a sustained duration version of NEUPOGEN was equal to that of multiple daily doses of NEUPOGEN.
CLT-008 may shorten the time to neutrophil recovery and decrease the risks of febrile neutropenia and infection.
Of the twelve subjects that received ProHema, the median time to neutrophil recovery (> 500 cells/[eth]-L) was 17.
CMX001 in the Peri-Engraftment Period Does Not Impair Neutrophil Recovery in Pediatric Allogeneic Hematopoietic Stem Cell Recipients," will be presented by Michael S.
CLT-008, a first-in-class, allogeneic cell-based therapy, is under development to provide hematopoietic support following high-dose chemotherapy or radiation exposure, by shortening the time to neutrophil recovery and decreasing the risks of febrile neutropenia and infection.
In addition, of the twelve subjects presented in the abstract that received a ProHema unit and an untreated unit, the median time to neutrophil recovery (> 500 cells/uL) was 17.
Filgrastim, or Neupogen, is commonly prescribed to speed neutrophil recovery in patients who receive cytotoxic chemotherapy, as well as to mobilize stem cells in patients planning to undergo autologous stem cell transplant or those who are acting as donors for people who will receive allogeneic stem cell transplants.
Seven patients experienced bone marrow suppression with a median time of 55 days (19-101) for neutrophil recovery.

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