neutropenic fever


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neutropenic fever

Fever associated with an abnormally low neutrophil level, usually caused by infection. This condition is treated with empirical antibiotic therapy pending the results of cultures. Neutropenia has many causes, including chemotherapy, radiation exposure, aplastic anemia, bone marrow infiltration from malignancy, and complications of bone marrow transplantation. The risk of potentially life-threatening infection is substantial when the absolute neutrophil count is below 500/ mm3.
See also: fever
References in periodicals archive ?
Pseudobacteraemia in a patient with neutropenic fever caused by a novel paenibacillus species: Paenibacillus hongkongensis sp.
An initial round of chemotherapy was given, but he developed neutropenic fever and ARDS and after a few days life support treatment was withdrawn.
The most common grade 3 and 4 adverse events that occurred were neutropenia (32 percent), neutropenic fever (11 percent) and anemia (11 percent).
Darinaparsin was very well tolerated with neutropenic fever as a severe adverse event in 1 patient.
In addition, the availability of newer broad spectrum antifungal agents with a good safety profile raise the possibility of using mold-active prophylaxis in patients at high risk for invasive fungal infections without the need to empirically modify antifungal therapy solely on persistent neutropenic fever of unknown etiology.
The most common adverse events were fever (85%), chills (73%), nausea (70%), vomiting (63%), asthenia (44%), diarrhea (38%), abdominal pain (37%), headache (35%), stomatitis (32%), dyspnea (32%), epistaxis (31%), hypokalemia (31%), anorexia (29%), sepsis (25%), constipation (25%), local reaction (25%), nonspecific rash (22%), herpes simplex (22%), and neutropenic fever (21%).