neutralization (redirected from neutralisation)

neu·tral·i·za·tion (ntr-l-zshn)

n.

1. A reaction between an acid and a base that yields a salt and water.

2. The rendering ineffective of an action or substance, such as a drug.

3. The change of an acid solution to neutral by titration of an alkaline solution.

4. The change of an alkaline solution to neutral by titration of an acid solution.

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neutralization

[-īzā′shən]

Etymology: L, neutralis + Gk, izein, to cause

the interaction between an acid and a base that produces a solution that is neither acidic nor basic. The usual products of neutralization are a salt and water. neutralize, v.

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neutralization,

n the reaction of an acid with a base.

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neutralization

the state of having been converted to neutrality from acid or base. Used also in microbiology to indicate neutralization of a toxin or of infectivity.

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neutralization tests

tests based on the ability of an antibody to neutralize the biological activity of an antigen. These may utilize antitoxins and toxins or immune serum and viruses or bacteria. The tests are often quantitative whereby antibody (serum) is serially diluted; the reciprocal of the highest dilution of serum neutralizing a standard amount of toxin or virus or bacteria is the neutralizing antibody titer of that serum.

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neutralization

1. A technique for determining the power of an ophthalmic lens. It is accomplished by placing a lens of known power and opposite sign in contact with the unknown lens and moved back and forth in a plane perpendicular to the line of sight until the observation of movement (against or with) of the distant image seen through the lenses disappear. The unknown lens will have the opposite power to that which neutralizes this apparent movement. 2. A method of breaking down hydrogen peroxide from a contact lens (mostly soft) following contact lens disinfection to avoid possible irritation to ocular tissues. This can be achieved by rinsing and dilution with saline, by using a solution with an enzyme catalase or a platinum disc incorporated into the lens case, or with a chemical agent such as sodium pyruvate or sodium thiosulfate. See disinfection; focimeter.