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neurotransmitter |
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neurotransmitter /neu·ro·trans·mit·ter/ (-tranz´mit-er) a substance released from the axon terminal of a presynaptic neuron on excitation, which diffuses across the synaptic cleft to either excite or inhibit the target cell.
false neurotransmitter an amine that can be stored in and released from presynaptic vesicles but that has little effect on postsynaptic receptors.
Neurotransmitter A chemical in the brain that transmits messages between neurons, or nerve cells. Changes in the levels of certain neurotransmitters, such as serotonin, norepinephrine, and dopamine, are thought to be related to bipolar disorder. Mentioned in: Alpha 1 -Adrenergic Blockers, Antidepressant Drugs, SSRI, Bipolar Disorder, Botulism, Central Nervous System Depressants, Club Drugs, Cocaine, Erectile Dysfunction, Intermittent Explosive Disorder, Lesch-Nyhan Syndrome, Lysergic Acid Diethylamide (LSD), Monoamine Oxidase Inhibitors, Mood Disorders, Neuroendocrine Tumors, Pain Management, Peripheral Neuropathy, Phototherapy, Premenstrual Syndrome, Tourette Syndrome, Weight Loss Drugs
neurotransmitter [-transmit′ər] Etymology: Gk, neuron + L, transmittere, to transmit a chemical that modifies or results in the transmission of nerve impulses between synapses. Neurotransmitters are released from synaptic knobs into synaptic clefts and bridge the gap between presynaptic and postsynaptic neurons. Each vesicle within a synaptic knob stores as many as 10,000 neurotransmitter molecules. When a nerve impulse reaches a synaptic knob, thousands of neurotransmitter molecules squirt into the synaptic cleft and bind to specific receptors. This flow allows an associated diffusion of potassium and sodium ions that causes an action potential. Excitatory neurotransmitters decrease the negativity of postsynaptic membrane potentials; inhibitory neurotransmitters increase such potentials. Kinds of neurotransmitters include acetylcholine, gamma-aminobutyric acid, and norepinephrine. neurotransmitter [noor″o-trans´mit-er] a substance (e.g., norepinephrine, acetylcholine, dopamine) that is released from the axon terminal of a presynaptic neuron on excitation, and that travels across the synaptic cleft to either excite or inhibit the target cell.
neurotransmitter (nerˈ·ō·transˑ·mi·ter), n chemical messenger that modifies or affects communication across synapses or neuromuscular connections. Important neurotransmitters include dopamine, serotonin, and acetylcholine.
neurotransmitter, n any one of numerous chemicals that modify or result in the transmission of nerve impulses between synapses. Neurotransmitters are released from synaptic knobs into synaptic clefts and bridge the gap between presynaptic and postsynaptic neurons.
neurotransmitter a substance (e.g. norepinephrine, acetylcholine, dopamine) that is released from the axon terminal of a presynaptic neuron on excitation, and which travels across the synaptic cleft to either excite or inhibit the target cell. adrenergic neurotransmitter see norepinephrine. neurotransmitter receptor
each neurotransmitter has its own receptor molecule; these show a high degree of structural homology. neurotransmitter A substance stored in the synaptic vesicles that is released when the axon terminal is excited by a nervous impulse. The substance then travels across the synaptic cleft to either excite or inhibit another neuron. This is accomplished by either decreasing the negativity of postsynaptic potentials (excitation), or increasing the negativity of postsynaptic potentials (inhibition). Common neurotransmitters include acetylcholine, dopamine, endorphins, adrenaline (epinephrine), gamma-aminobutyric acid (GABA), amino acids, such as glutamate and glycine, noradrenaline (norepinephrine), serotonin and substance P. Common neurotransmitters in the retina are glutamate (the primary excitatory neurotransmitter), GABA (inhibitory), glycine (inhibitory), dopamine (excitatory) and acetylcholine (excitatory). See neuron; synapse.
neurotransmitter Neurosynaptic transmitter Physiology Any of a number of small neuroregulating molecules–eg, catecholamines and acetylcholine, which are synthesized in the presynaptic terminals of neurons, stored in vesicles, and cause
rapid and transient depolarization near their point of release in the synaptic cleft, where it stimulates production of either excitatory or inhibitory postsynaptic potentials; neurotransmission at synapses or neuromuscular junctions is due to
binding of a neurotransmitter to its cognate receptor. See Amino acid neurotransmitter, Neuropeptide, Neuroregulator. Cf Hormone. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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