neurotoxicity


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Related to neurotoxicity: Glutamate neurotoxicity

neurotoxicity

 [noor″o-tok-sis´ĭ-te]
the ability to exert a destructive or poisonous effect upon nerve tissue. adj., adj neurotox´ic.

neurotoxicity

/neu·ro·tox·ic·i·ty/ (noor″o-tok-sis´it-e) the quality of exerting a destructive or poisonous effect upon nerve tissue.neurotox´ic

neurotoxicity

[-toksis′itē]
Etymology: Gk, neuron, nerve, toxikon, poison
the ability of a drug or other agent to destroy or damage nervous tissue.

neurotoxicity

The degree to which a substance, including a therapeutic agent, can damage the nervous system.

neurotoxicity

the quality of exerting a destructive or poisonous effect upon nerve tissue.
References in periodicals archive ?
We tried to analyse how metals affect neurotoxicity and the implications.
Moreover, since neurotoxicity frequently requires early termination of cisplatin therapy, the use of vitamin E might actually enhance the anticancer effect of the treatment by allowing for a higher cumulative cisplatin dose.
a persistent sensory neurotoxicity that is characterized by progressive and cumulative deficits.
The incidence of grade 2 or 3 neurotoxicity was higher in the combination therapy group (11.
It has been reported that intrathecal ropivacaine might be neurotoxic (11-13), so further study of ropivacaine neurotoxicity is warranted.
The drug, which has disease-modifying potential by preventing metal-dependent aggregation, neurotoxicity and deposition of beta amyloid, has been tested in human Phase I trials for safety and tolerability at various doses and different durations in a total of 90 elderly, healthy volunteers.
The study was projected for a larger number of patients with a 2x2 factorial design to also study the influence of calcium and magnesium on oxaliplatin neurotoxicity.
To date, there are only seven reported cases of baclofen-induced neurotoxicity in patients with renal failure, including ours (Table).
PAION expects that the lead will be tested for lack of neurotoxicity during 2006.
Other early signs of opioid neurotoxicity are hypervigilance and hyperalgesia.