neuroprotective agent

Neurology Any agent or drug that protects the brain from secondary injury caused by stroke. See Stroke.

References in periodicals archive ?

Experimental evidence of Ginkgo biloba extract EGB as a neuroprotective agent in ischemia stroke rats.

Pretreated Glehnia littoralis Extract Prevents Neuronal Death Following Transient Global Cerebral Ischemia through Increases of Superoxide Dismutase 1 and Brain-derived Neurotrophic Factor Expressions in the Gerbil Hippocampal Cornu Ammonis 1 Area

Conclusions: Our finding suggest that metformin exposure attenuates PTZ-induced neuronal cell death may act as a safe therapeutics and neuroprotective agent for the treatment of neuronal loss as result of seizure.

Metformin attenuate PTZ-induced apoptotic neurodegeneration in human cortical neuronal cells

Safety and efficacy of dextromethorphan as neuroprotective agent in the evolution of patients in acute phase of ischemic stroke).

NEU-001: Seguridad y eficacia del dextrometorfano como agente neuroprotector en la evolucion de pacientes en la fase aguda del ictus isquemico

Is phenobarbital a neuroprotective agent in newborn infants with perinatal asphyxia?

Effect of phenobarbital on nitric oxide level in term newborn infants with perinatal asphyxia

To simulate the in vivo CNS environment, we treated N2a cells with LNE-treated BV2 conditioned medium and found that it inhibited the expression of apoptotic proteins and increased the viability of N2a cells, suggesting that LNE is a potential neuroprotective agent.

Anti-neuroinflammatory and neuroprotective effects of the Lindera neesiana fruit in vitro

Many Phase III trials are required before the implication of GCSF as neuroprotective agent in the treatment of stroke opening a new era for the treatment of this devastating disease.

Granulocyte-Colony Stimulating factor for mobilizing bone marrow stem cells in the Sub acute Stroke.How safe is the use of Granulocyte-colony stimulating factor in sub-acute stroke? Isthis stem cell trial of recovery enhancement beneficial?

These results demonstrate that GTPs may act as a potential neuroprotective agent against BBB damage at the early stage of focal cerebral ischemia through the regulation of TJ and PKCasignaling.

Green tea polyphenols alleviate early blood brain barrier damage during experimental focal cerebral ischemia through regulating tight junctions and PKCalpha signalling

inability to control for the inclusion of magnesium sulfate in more recent trials, when it was classified as a neuroprotective agent and not a tocolytic

Which tocolytic agents are most likely to delay delivery and improve neonatal outcomes?

Parkin is a broad neuroprotective agent that acts against a wide range of toxic insults, including those that are not part of the ubiquitin-proteasome system.

Parkin and Parkinson disease

PBT434 is a neuroprotective agent designed to prevent or slow the loss of the neurons of the substantia nigra that produce the chemical dopamine, the neurotransmitter that controls motor function in the brain.

Prana gets US patent for PBT434 Parkinson's drug candidate

Lead researcher Dr Xiang Gao, from the Harvard School of Public Health in Boston, Massachusetts, said: "Our findings suggest that ibuprofen could be a potential neuroprotective agent against Parkinson's disease, however the exact mechanism is unknown.

Painkiller 'protects against Par kinson's' Ibuprofen may slow progress of the disease

The promising results of the trial suggest that further investigation into the extract as a neuroprotective agent is warranted.