neuronal nitric oxide synthase


Also found in: Acronyms.

neuronal nitric oxide synthase

the constitutive isoform of nitric oxide synthase found within neurons.
See also: nitric oxide synthase, nitric oxide.

neuronal nitric oxide synthase

See nNOS.
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References in periodicals archive ?
Neuronal nitric oxide synthase within paraventricular nucleus: blood pressure and baroreflex in two-kidney, one-clip hypertensive rats.
Rat basal forebrain cholinergic lesion affects neuronal nitric oxide synthase activity in hippocampal and neocortical target regions.
Excessive production of nitric oxide by neuronal nitric oxide synthase (nNOS) subsequent to calcium influx through NMDARs is thought to be a major factor contributing to stroke-induced neuronal damage (Lee et al.
Indeed, neuronal nitric oxide synthase (nNOS) was shown to be involved in various behavioral abnormalities, including ADHD [7, 8].
NXN-188 is a dual action new chemical entity which incorporates a novel mechanism, selective inhibition of neuronal Nitric Oxide Synthase (nNOS), as well as 5-HT1B/1D activation - the mechanism of triptans, the largest class of migraine drugs.
a development-stage pharmaceutical company that is designing and developing next-generation pain therapeutics targeting neuronal nitric oxide synthase (nNOS), today announced that NXN-188, a novel oral selective nitric oxide synthase inhibitor and 5HT agonist in development for acute migraine, has been selected as one of the Top 10 most promising neuroscience projects currently available for strategic partnering.
a development-stage pharmaceutical company that is designing and developing next-generation pain therapeutics targeting neuronal nitric oxide synthase (nNOS), today announced that it has closed a convertible debenture financing in which the convertible debentures are convertible under specified circumstances into existing class B preferred shares for a total of approximately $14 million.
NeurAxon is focused on the discovery and development of next-generation pain therapeutics targeting neuronal nitric oxide synthase (nNOS), an enzyme involved in modulating pain and central nervous system neuronal sensitization.
a developer of next-generation pain therapeutics targeting neuronal nitric oxide synthase (nNOS), today announced that NXN-188, a novel oral selective nitric oxide synthase inhibitor and 5HT agonist in development for migraine with aura, has been selected as one of the Top 10 most promising neuroscience projects currently available for strategic partnering.

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