neuronal intestinal dysplasia
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increased numbers of ganglion cells with myenteric plexus hyperplasia and increased acetylcholinesterase activity in nerves of the mucosa and submucosa. Clinically, neuronal hyperplasia mimics Hirschsprung disease. Similar findings are seen in patients with multiple endocrine neoplasia syndrome, type IIB, and in neurofibromatosis.
neuronal intestinal dysplasiaAbbreviation: NID
A disorder of bowel motility in which the innervation of the intestines is ectopic (the ganglions that provide nervous control of intestinal musculature being misplaced).
See also: dysplasia