neuromyelitis optica

Also found in: Dictionary, Acronyms, Encyclopedia, Wikipedia.


inflammation of nervous and medullary substance; myelitis attended with neuritis.
neuromyelitis op´tica combined demyelination of the optic nerve and spinal cord, with diminution of vision and possible blindness, flaccid paralysis of extremities, and sensory and genitourinary disturbances.

neu·ro·my·e·li·tis op·'ti·ca

a demyelinating disorder consisting of a transverse myelopathy and optic neuritis.
Synonym(s): Devic disease

neu·ro·my·e·li·tis op·ti·ca

(nūr'ō-mī-ĕ-lī'tis op'tik-ă)
A demyelinating disorder consisting of a transverse myelopathy and optic neuritis.
Synonym(s): Devic disease.

neuromyelitis optica

An acute nervous system disorder featuring DEMYELINATION of the tracts in the nerve tracts in the spinal cord and both optic nerves. The condition occurs about a week after an attack of measles or chickenpox or may follow vaccination. There is headache, vomiting, stiff neck, paralysis and blindness and the death rate is high. In those who survive, recovery is often surprisingly complete. Also known as Devic's disease. (Eugene Devic, 1858–1930, French physician).


Eugène, French physician, 1869-1930.
Devic disease - a demyelinating disorder consisting of a transverse myelopathy and optic neuritis. Synonym(s): neuromyelitis optica
References in periodicals archive ?
Variants of CYP27B1 are associated with both multiple sclerosis and neuromyelitis optica patients in Han Chinese population.
Presence of anti-Ro/SSA antibody may be associated with anti-aquaporin-4 antibody positivity in neuromyelitis optica spectrum disorder.
Immunosuppressive therapy is more effective than interferon in neuromyelitis optica," Multiple Sclerosis, vol.
A review of the Neuromyelitis Optica (Devic's Syndrome) products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
Neuromyelitis optica in France: a multicenter study of 125 patients.
Neuromyelitis Optica Preceded by HypercKemia and a Possible Association with coxsackie Virus Group A10 Infection.
In the new guidelines, "we wanted to encompass all patients who would have previously been diagnosed as having neuromyelitis optica or NMOSD," he said.
Autoimmune/idiopathic Multiple sclerosis (MS) Acute disseminated encephalomyelitis (ADEM) Neuromyelitis optica (NMO) Acute transverse myelitis (ATM) Subacute sclerosing panencephalitis (SSPE) 2.
Wingerchuk, Neuromyelitis Optica Spectrum Disorders.
Tyrese was just three years-old when he was diagnosed with the most aggressive form of neuromyelitis optica (NMO).
The panel focused on the differential diagnosis for MS of neuromyelitis optica (NMO) and NMO spectrum disorders, because "there is increasing evidence of relapsing CNS demyelinating disease characterized by involvement of optic nerves (unilateral or bilateral optic neuritis), often severe myelopathy with MRI evidence of longitudinally extensive spinal cord lesions, often normal brain MRI (or with abnormalities atypical for MS), and serum aquaporin-4 (AQP4) autoantibodies.