Nevertheless, after this stage, longstanding biochemical, biomechanical, neurohumoral
, and inflammation responses lead to structural damage of the pancreas (chronic pancreatitis) and a lowering of the exocrine pancreatic function while bringing many accompanying digestive diseases.
and haemodynamic profile in postural tachycardia and chronic fatigue syndromes.
His overarching scientific interest has been the neurohumoral
axis and its role in the pathophysiology and treatment of heart failure.
Such comorbidities may induce secondary neurohumoral
activation due to mechanical stretch and associated cellular stress, with subsequent release of cardiac troponin into the circulation.
antagonists, an ACEI (or angiotensin receptor blocker (ARB)), a beta-blocker (BB) and MRAs are fundamentally important in modifying the course of HF-REF and should be considered in every patient.
Other mechanisms such as neurohumoral
or metabolic, may be played role in this case.
A number of pathways are important for the development of obesity and/or diabetes, including but not limited to alterations in neurohumoral
signaling, feeding behavior, energy balance, brain and peripheral inflammation, and insulin resistance.
features of myocardial stunning due to sudden emotional stress.
Despite the substantial differences in the EF, Both groups have reductions in exercise tolerance, neurohumoral
activation, and abnormal left ventricular (LV) filling dynamics and impaired relaxation and have similar clinical symptoms and signs.
Recently, lots of experiments have verified the effect of central nervous system (CNS) on fatigue, cerebral metabolic and neurohumoral
alterations during strenuous exercise may result in the impairment of cortex activity, and this may lead to the failure of CNS sustaining adequate central drive to spinal motoneurons (Davis and Bailey, 1997).
Currently, the most prominent theories suggest that CD may be caused by direct mechanical stimulation of the myocardium or a neurohumoral
response to treatment or both.
The etiopathogenesis is still obscure although there are many hypotheses including neurohumoral