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neurofibrillary tangle |
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Neurofibrillary tangle
—Twisted masses of protein inside nerve cells that develop in the brains of people with AD. Mentioned in: Alzheimer's Disease
neurofibrillary tangle Neuropathology A characteristic histologic finding in the perikaryon of large cortical neurons of Pts with Alzheimer's disease, the number of NFTs loosely correlates with the severity of dementia DiffDx
Down's syndrome, subacute sclerosing panencephalitis, lead encephalopathy, tuberous sclerosis, Hallervorden-Spatz disease, lipofuscinosis, post-encephalitic parkinsonism, and normal adults–confined to the hippocampus. Cf
Alzheimer's disease, Amyloid plaque, Granulovacuolar degeneration, Paired helical filaments, Senile plaques. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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