neurodegenerative disorder

neurodegenerative disorder

Neurology A chronic progressive neuropathy characterized by selective and generally symmetrical loss of neurons in motor, sensory, or cognitive systems Types by area Cerebral cortex–Alzheimer's disease, Pick's disease, Lewy body dementia Basal ganglia–Huntington's disease, Parkinson's disease Brainstem & cerebellum–dentatorubropallidoluysian atrophy, Freidreich's ataxia, multiple system atrophy, types 1, 2, 3, 6, 7 spinocerebellar ataxia Motor–amyotrophic lateral sclerosis, familial spastic paraparesis, spinal muscular atrophy, spinal & bulbar muscular atrophy. See COPD.
References in periodicals archive ?
The use of transplanted fetal brain tissue to replace brain cells lost in Parkinson's disease patients has proved promising enough that researchers have begun to test the strategy on people with Huntington's disease, another neurodegenerative disorder.
Huntington's disease is a fatal neurodegenerative disorder characterized by involuntary movements, loss of cognitive function and memory, and a wide spectrum of behavioral disorders.
Huntington's disease, a fatal neurodegenerative disorder, stems from an unusual mutation in which a gene becomes too big for its own good.
Apoptosis may also play a role in amyotrophic lateral sclerosis (ALS), the neurodegenerative disorder better known as Lou Gehrig's disease.
The new finding raises the hope that the same protein may help people suffering from this neurodegenerative disorder, characterized by a shuffling walk, rigidity, and tremors.
ALS is a progressive and fatal neurodegenerative disorder affecting over 30,000 patients in the U.
The extensive test set validated study shows clearly that the gene expression signature identified by DiaGenic can distinguish, with high accuracy, individuals with AD from both healthy elderly and younger individuals and also from those with another neurodegenerative disorder, Parkinson disease.
In 1993, researchers learned that this fatal neurodegenerative disorder results from unexplained genetic stutters, expansions in the size of a particular gene.
Alzheimer's disease is a debilitating neurodegenerative disorder characterized by progressive loss of memory and cognitive function, affecting 4.
Using mutant proteins from people with Huntington's disease as bait, investigators have reeled in a novel brain protein that may play a role in this neurodegenerative disorder.
Adding to the suspicion that learning involves synelfin, Clayton's group notes two possible links between the protein and Alzheimer's disease, a neurodegenerative disorder that ravages memory.
Last, in historically low-incidence areas where Lyme disease has since spread, any potential time lag between infection and development of a neurodegenerative disorder would reduce the observed correlation in these areas.