Our case report emphasizes that neurobrucellosis
should be considered in evaluation of patients with unexplained neurological symptoms.
A final diagnosis of neurobrucellosis
with pseudotumor cerebri was established.
is a severe but rarely seen complication of human brucellosis.
ELISA versus routine tests in the diagnosis of patients with systemic and neurobrucellosis
is uncommon, developing in <5% of patients with Brucella infection and producing diverse neurological syndromes.
Invasive brucellosis and neurobrucellosis
will require prolonged treatment (2-12 months) with a combination of intravenous rifampin, doxycycline, and gentamicin for a week or more followed by six or more weeks of oral doxycycline and rifampin.
He had a history of using antibiotics with the suspicion of neurobrucellosis
just because brucellosis is endemic in our country.
should be considered in long term fever accompanying the unexplained neurological symptoms such as hearing loss.
Three cases were attributed to environmental exposures (3,4); two of the patients reported symptoms consistent with neurobrucellosis
, and the third was diagnosed with spinal osteomyelitis.
Nervous system involvement, known as neurobrucellosis
(NB), occurs in about 2-10% of the cases and can develop at any stage of the disease (2,4-6).
Utility of the enzyme-linked immunosorbent assay for diagnosing neurobrucellosis
More severe complications comprise, in descending order of frequency, neurobrucellosis
, liver abscesses, and endocarditis (FUGIER et al.