neuraminic acid


Also found in: Encyclopedia, Wikipedia.

sialidase

 [si-al´ĭ-dās]
1. an enzyme of the hydrolase class that catalyzes the cleavage of glucosidic linkages between a sialic acid residue and a hexose or hexosamine residue at the nonreducing terminal of oligosaccharides in glycoproteins, glycolipids, and proteoglycans. Deficiency of it is an autosomal recessive trait and is seen in sialidosis and galactosialidosis.
2. the enzyme with this activity specifically cleaving sialic acid–containing gangliosides; it is deficient in mucolipidosis IV. Called also neuraminidase.

neur·a·min·ic ac·id

(nūr'ă-min'ik as'id),
An aldol product of d-mannosamine and pyruvic acid, linking the C-1 of the former to the C-3 of the latter. The N- and O-acyl derivatives of neuraminic acid are known as sialic acids and are constituents of gangliosides and of the polysaccharide components of mucoproteins and glycoproteins from many tissues, secretions, and species.
Synonym(s): prehemataminic acid

neuraminic acid

/neu·ra·min·ic ac·id/ (noor″ah-min´ik) a 9-carbon amino sugar whose N- acyl derivatives are the sialic acids.

neuraminic acid

[noor′ah-min′ik]
a nine-carbon amino acid formed from mannosamine and pyruvate. See also sialidase.

neu·ra·min·ic ac·id

(nūr'ă-min'ik as'id)
An aldol product of d-mannosamine and pyruvic acid. The N- and O-acyl derivatives of neuraminic acid are known as sialic acids and are constituents of gangliosides and of the polysaccharide components of muco- and glycoproteins from many tissues and secretions.

neuraminic acid

a nine-carbon sugar; parent of a family of amino sugars containing nine or more carbon atoms (the sialic acids or nonulosaminic acids).
References in periodicals archive ?
A naturally occurring deaminated neuraminic acid, 3-deoxy-D-glycero-D-galacto-nonulosonic acid (KDN).
Rapid analysis of O-acetylated neuraminic acids by matrix assisted laser desorption/ionization time-of-flight mass spectrometry.
N-acetyl neuraminic acid and papain were obtained from Sisco Research Laboratory (Bombay).
Sialic acid content was determined from the standard graph plotted using n-acetyl neuraminic acid.
It has an important role in the synthesis of N-acetyl neuraminic acid (Sialic acid), which is a component of glycolipids present on the surface of tumor cells (Voet and Voet, 1995).
2]-transferrin ([beta]2Tr) r-fraction, or asialotransferrin, is a brain-specific variant of transferrin that lacks neuraminic acid.
The spectrum of free neuraminic acid storage disease in childhood: clinical, morphological and biochemical observations in three non-Finnish patients.