neural tube defects


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neural tube defects

See SPINA BIFIDA and ANENCEPHALY. See also FOLIC ACID.

Neural tube defects

A group of birth defects that affect the backbone and sometimes the spinal chord.
Mentioned in: Birth Defects
References in periodicals archive ?
International retrospective cohort study of neural tube defects in relation to folic acid recommendations: are the recommendations working?
A graph of the rates of neural tube defects per 10,000 births, from 1988 to 1998, showed virtually no change, at around seven instances per 10,000 births, for pregnancies in England and Wales in the period after the Government started promoting folic acid.
And added: 'From these data, we estimate that thousands of pregnancies that would otherwise have been healthy were affected by neural tube defects in the study area alone since 1992.
The team from Queen Mary University of London concluded that an "upper intake level is therefore unnecessary and should be removed", and described the pregnancies affected by neural tube defects as a "completely avoidable tragedy".
A first to evaluate the relationship between low carbohydrate intake and having children with neural tube defects, the study was led by Tania Desrosiers, PhD, MPH, and research assistant professor of epidemiology at the UNC Gillings School of Global Public Health.
Updated estimates of neural tube defects prevented by mandatory folic Acid fortification--United States, 1995-2011.
gov/news-events/news-releases/low-levels-vitamin-b12-may-increase-risk-neural-tube-defects) 2009 study on the risks of vitamin B12 deficiency conducted by researchers at the National Institutes of Health, Trinity College, Dublin, and Health Research Board of Ireland, found that women who do not get enough vitamin B12 during early pregnancy are five times more likely to face the risk of having a child with a neural tube defect, a class of birth defect, as compared to those women who have a higher intake and level of the vitamin in their bodies.
Increased consumption of folic acid in enriched flour has been helpful in reducing the incidence of neural tube defects in the general population, said Susan Mayne, Ph.
When most physicians and patients hear about folic acid, they automatically think about its role in preventing spina bifida and other neural tube defects.
C677T polymorphism of the methylentetrahydrofolate reductase gene in mothers of children affected with neural tube defects.
The Centers for Disease Control and Prevention's recent report updating the estimated number of neural tube defects prevented by folic acid fortification of enriched cereal grain products clearly shows the huge impact of fortification: From 1999 through 2011, fortification prevented neural tube defects in about 1,300 births a year in the United States (MMWR 2015;64:1-5).