neural crest cell


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neural crest cell

Embryonic cells of the neuron-glia lineage that form along the ridges (neural folds) of the neural plate and that migrate into the developing organism to produce a variety of tissues. The migratory ability of these embryonic epithelial cells is similar to the motility of mesenchyme cells; this has led neural crest cells to be called mesectodermal cells. In the neural lineage, neural crest cells give rise to the dorsal root ganglia, the placodes that will develop into the olfactory and auditory sensory organs, the pituitary gland, the peripheral autonomic nervous system, and the neurenteric and APUD cells. In the glial lineage, neural crest cells give rise to Schwann cells and other peripheral satellite cells. In addition, neural crest cells of the cranial region give rise to certain facial connective tissue, including the bones of the nasal cavities, the roof of the mouth, and the sella turcica.
See also: cell
References in periodicals archive ?
Title: Epithelial-Mesenchymal Transition and Cellular Migration in Neural Crest Cells and Metastatic Carcinoma Cells.
Origins and plasticity of neural crest cells and their roles in jaw and craniofacial evolution.
Lack of beta1 integrins in enteric neural crest cells leads to a Hirschsprung-like phenotype.
The winged-helix transcription factor Foxd3 suppresses interneuron differentiation and promotes neural crest cell fate.
Often the protocols provide low yields, making the isolation of the desired neural crest cells a time-consuming and technically challenging process.
Five of those genes are involved in controlling survival and migration of neural crest cells in the embryo.
The neural crest cell defects are probably the result of changes in dozens of genes, each producing a small effect on the cells' behavior, the team proposes.
September 19, 2012 -- Researchers have developed a stable population of neural crest cells derived from mice that can be grown in large quantities in the laboratory and that demonstrates the potential to develop into many different cell types needed throughout the body.
The Johns Hopkins researchers say their work substantially expedites the creation of neural crest cells from any patient with a neural crest-related disorder, a tool that lets physicians and scientists study each patient's disorder at the cellular level.
When those neural crest cells were subjected to conditions mimicking a transient fever, the embryos developed craniofacial irregularities and heart defects, including double outlet right ventricle, Tetralogy of Fallot and other outflow obstructions.
Thymus is a primary lymphoid organ derived from the third pharyngeal pouch under the inductive effect of neural crest cells.
March 15, 2017 -- Researchers here have demonstrated that adult skin cells can be converted into neural crest cells (a Type of stem cell) without any genetic modification, and that these stem cells can yield other cells that are present in the spinal cord and the brain.