nerve fibre

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nerve fibre

the AXON of a NERVE (1) together with its surrounding membranes.
Part of a myelinated nerve fibre.

nerve fibre

component of all nerves and their branches in the peripheral nervous system (PNS), and of the tracts in the central nervous system (CNS). The central axontransmits nerve impulses (action potentials) to the nerve terminal in motor (efferent) nerves, or from a receptor to a nerve cell body in sensory (afferent) nerves. Also common to all nerve fibres are an outermost covering (neurilemma) and within that the Schwann cells which are crucial to the regeneration process if a fibre is damaged. In myelinated nerve fibres (including motor nerves to skeletal muscle) there is a fatty myelin sheath between the axon and the neurilemma, interrupted at intervals by the 'nodes of Ranvier'; action potentials 'jump' between these, enabling faster conduction. Each efferent nerve fibre runs from a nerve cell body to terminal branches at a nerve-to-nerve synapse or at an effector organ; each afferent fibre runs from a sensory receptor to a relay site in the CNS.
References in periodicals archive ?
DISCUSSION: A study of 5, 789 patients found myelinated nerve fibres in 0.
Following the onset of arthritis in the rats, however, these fibres began to sprout into the inflamed skin over the joint and wrap around the pain-sensing nerve fibres instead.
They showed that the nerve fibres could be guided to their correct targets using a particular growth factor - a biological chemical that promotes growth.
Generally there are still some nerve fibres that are undamaged.
Instead the study found that long nerve fibre connections were just as vital as short ones.
The damage disrupts messages travelling along nerve fibres, either slowing them down, distorting them, preventing them from getting through and short circuiting them.
The team, led by Dr Georgio Terenghi at the Royal Free Hospital in London, has just started growing nerve fibres through the polymer tubes in the laboratory.
Visual acuity is usually not affected in these cases; however Patient may have relative scotomas if sufficient number of myelinated nerve fibres are present.
Unfortunately, as people with MS age, remyelination decreases significantly, resulting in more nerve fibres being permanently lost.
The breakthrough came after tests on adult rats, conducted by a team of scientists based at the National Institute for Medical Research, confirmed that severed nerve fibres located in the spinal cord could be reunited with the brain.
Tests on adult rats, by a team of scientists based at the National Institute for Medical Research, confirmed severed nerve fibres could be re-engaged with the brain.
The source of the increased CGRP was thought to be certain types of sensory nerve fibres in the skin that normally make and release a type or "isoform" called CGRP-alpha.