Our preliminary study showed maximum nephrotoxicity
after 16 days of gentamicin injection, which stayed high up to the end of the treatment period.
This dose has already been shown to produce nephrotoxicity
There is concern that in sub-Saharan Africa the risks of tenofovir nephrotoxicity
may be greater because of the high background prevalence of renal disease, including HIV-associated nephropathy, and lack of capacity to monitor renal function regularly.
The present study compared the effect of ET-1 antagonist bosentan and the new antagonist macitentan, also called actelion-1 or ACT-064,922, in the nephrotoxicity
induced by CsA in hypertensive rats.
In group E, coadministration of amphotericin B and cyclosporine resulted in marked nephrotoxicity
as evident from acute rise in blood urea, serum creatinine, hyponatremia and hyperkalemia, and marked, grade-3 necrosis of renal tubules (fig-1 and 2).
Comment: The results of this study are consistent with other research demonstrating that prophylactic administration of intravenous magnesium can prevent cisplatin-induced nephrotoxicity
without interfering with the anticancer effect of chemotherapy.
Biologic markers of oxidative stress and nephrotoxicity
as studied in biomonitoring of adverse effects of occupational exposure to lead and cadmium.
1 However, CP can be toxic and cause severe side effects leading to nephrotoxicity
,2 hepatotoxicity,3 reproductive system toxicity4 and cardiotoxicity.
The mean duration of development of nephrotoxicity
Background fluctuation of kidney function versus contrast-induced nephrotoxicity
were said to induce significantly when serum creatinine values were >0.
was defined as a rise in [S.