effect of aqueous extract of Allium sativum bulbs has been attributed to attenuation of vascular endothelial growth factor and extracellular signal-regulated kinase-1 expression in diabetic rats (Shiju et al.
It is therefore advisable to use combination ARB/ACE-I therapy in more complex cases to obtain a greater nephroprotective
lactiflora (containing paeoniflorin, oxypaeoniflorin, benzoylpaeoniflorin, benzoyloxypaeoniflorin, oxybenzoylpaeoniflorin, albiflorin, paeoniflorigenone and lactiflorin) has nephroprotective
effects in murine models of diabetes.
3,7) The effectiveness of the prophylactic use of nephroprotective
drugs such as acetylcysteines remains uncertain, and consistent protection has not been proven in the reports investigating the usefulness of these drugs.
and hepatoprotective effects of curcuminoids.
There is some evidence that rosuvastatin is nephroprotective
, as demonstrated by the fall in the serum creatinine level in many patients after institution of rosuvastatin therapy.
But not all agents in each class have been studied specifically for their nephroprotective
VTP-27999 demonstrated significant nephroprotective
effects in preclinical in vivo studies, including a clear survival benefit.
It indicated that loganin ameliorates renal function not by reducing blood sugar levels, but direct nephroprotective
Various scientific studies have reported on the hepatoprotective, nephroprotective
and protection against oxidative stresses activities of the plant.
Sulodexide belongs to a proposed new class of nephroprotective
, or kidney protecting, drugs, known as the glycosaminoglycans.
Greater attention must be paid" to preventing hypotension and renal failure in women by minimizing the amount of contrast agent that is used and by using nephroprotective