neovascularization


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Related to neovascularization: Corneal neovascularization

neovascularization

 [ne″o-vas″ku-lar-ĭ-za´shun]
1. new blood vessel formation in abnormal tissue or in abnormal positions; see also angiogenesis.

ne·o·vas·cu·lar·i·za·tion

(nē'ō-vas'kyū-lar-i-zā'shŭn),
Proliferation of blood vessels in tissue not normally containing them, or proliferation of blood vessels of a different kind than usual in tissue.

neovascularization

The formation of new blood vessels–ie, capillary ingrowth and endothelial proliferation in unusual sites, a finding typical of so-called 'angiogenic diseases,' which include angiogenesis in tumor growth, diabetic retinopathy, hemangiomas, arthritis, psoriasis

ne·o·vas·cu·lar·i·za·tion

(nē'ō-vas'kyū-lar-ī-zā'shŭn)
Proliferation of blood vessels in tissue not normally containing them, or proliferation of blood vessels of a different kind than usual in tissue.

Neovascularization

Abnormal or excessive formation of blood vessels as in some retinal disorders.

vascularization

; neovascularization new blood vessel formation

neovascularization

Development of new blood vessels, especially in tissues where circulation has been impaired by disease or trauma.
choroidal neovascularization (CNV) Abnormal growth of blood vessels, originating in the choriocapillaris, which pass through Bruch's membrane and then proliferate under the retinal pigment epithelium (type 1) and/or under the retina (type 2). It may occur as a result of a rupture of Bruch's membrane, release of cytokines (e.g. VEGF), inflammation, oxidative stress to the retinal pigment epithelium, or vascular insufficiency. The condition is the main cause of exudative (wet) age-related macular degeneration and it may be associated with various disorders including angioid streaks, choroidal rupture, pathological myopia, chorioretinal scars and birdshot retinochoroidopathy. See age-related macular degeneration.
corneal neovascularization See pannus.
iris neovascularization Abnormal formation of new blood vessels on the anterior surface of the iris. It is commonly associated with many conditions that have led to retinal ischaemia, such as diabetic retinopathy, occlusion of the central retinal vein, carotid arterial disease, uveal melanoma, long-standing retinal detachment, etc. The neovascularization begins at the pupil margin and often at the same time in the angle of the anterior chamber and spreads over the whole surface. New vessels are associated with fibrous tissue membranes, which may block the passage of aqueous humour through the trabecular meshwork (neovascular glaucoma) and ectropion uveae near the pupillary margin. Treatment typically includes photocoagulation to prevent the formation of new blood vessels.

neovascularization

formation of new blood vessels.
References in periodicals archive ?
High volume ultrasound-guided injections also target the neovascularization in abnormal tendons similar to sclerosing injections.
Iris neovascularization was associated with undifferentiated tumor (P = .
By week 3, all 10 patients treated with pegaptanib showed a marked regression of retinal neovascularization (nine total, one partial), as assessed by slit-lamp biomicroscopy, fundus photography, and fluorescein angiography.
However, in studies conducted both in mice and in heart attack patients, the Weill Cornell team discovered that tenascin-C also reappears in and around the heart to help guide clot-induced neovascularization.
Scientists are looking at a wide variety of therapies and agents to stop the neovascularization process, according to Dr.
We infer, therefore, that STSM has a direct effect on the retinal capillary of posterior ocular region and suppresses neovascularization of retinal capillary in STZ diabetic rats through the activation of tetrandrine.
This technique uses the heat of a laser to coagulate, or seal off, the leaky vessels that occur in neovascularization, preventing future bleeds from the treated vessels.
Global Markets Direct's, 'Corneal Neovascularization - Pipeline Review, H2 2012', provides an overview of the indication's therapeutic pipeline.
com adds "Corneal Neovascularization - Pipeline Review, H1 2015" to its store.
Neovascularization is the process of new blood vessel formation from existing vasculature and occurs in the tissue-implant interaction.
Shusheng Wang, assistant professor of ophthalmology and pharmacology and co-senior author of the study and colleagues found that silencing the microRNA cluster members miR-23 and miR-27 hindered the excessive formation of blood vessels in the back of the eye, known as choroidal neovascularization.
The purpose of the present study was to investigate the effect of AST on the development of experimental choroidal neovascularization (CNV) with underlying cellular and molecular mechanisms.