neostigmine /neo·stig·mine/ (-stig´mēn) a cholinergic (cholinesterase inhibitor), used as the bromide or methylsulfate salt in the treatment of myasthenia gravis, in the prevention and treatment of postoperative stasis and atony of the gastrointestinal tract or urinary bladder, and for postsurgical reversal of the effects of nondepolarizing neuromuscular blocking agents.
neostigmine
ne·o·stig·mine (n   -st g mn, -mn)n. A drug that inhibits acetylcholinesterase, used in its bromide form orally and its methylsulfate form parenterally to treat myasthenia gravis. |
neostigmine
an anticholinesterase used in the treatment of myasthenia gravis and glaucoma and as an antidote for nondepolarizing muscle relaxants, such as tubocurarine.
neostigmine test
muscle weakness caused by myastenia gravis is temporarily reversed following the administration of neostigmine; used as a diagnostic test.
neostigmine
A reversible anticholinesterase drug, which neutralizes the effect of acetylcholinesterase and thereby allows the prolonged action of acetylcholine on the iris and ciliary muscle. Its action is similar to physostigmine but it is not so irritating a miotic. Both are occasionally used in the treatment of glaucoma. See acetylcholine; parasympathomimetic; physostigmine; miosis; miotics.
neostigmine
Pharmacology An anticholinesterase used for the symptomatic therapy of myasthenia gravis and, in anesthesiology, to reverse the effects of depolarizing agents. See Myasthenia gravis, Reversal agent.
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