neonatal withdrawal syndrome

neonatal withdrawal syndrome

Neonatal abstinence syndrome Neurology A condition affecting infants of mothers who chronically used CNS-active substances during pregnancy, for which the infant developed an in utero tolerance and who, on delivery, undergoes withdrawal Agents Opioids–eg, heroin, methadone, meperidine, codeine, pentazocine, propoxyphene, crack cocaine, alcohol, clomipramine, sedative-hypnotics–
eg, barbiturates, meprobamate, benzodiazepines Clinical Wakefulness, irritability, seizures, tremulousness, lability of temperature, tachypnea, hyperacusis, hyperreflexia, hypertonicity, diarrhea, sweating, respiratory distress and apnea, rhinorrhea, autonomic dysfunction, respiratory alkalosis, lacrimation, yawning, sneezing; Sx appear 12 h to 1 wk after birth Treatment Swaddling–firmly wrapping in blankets, ↓ external stimuli, tincture of opium. See Crack babies.