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neonatal hepatitis

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hepatitis /hep·a·ti·tis/ (hep″ah-ti´tis) pl. hepati´tides   Inflammation of the liver.
hepatitis A  a self-limited viral disease of worldwide distribution, usually transmitted by oral ingestion of infected material but sometimes transmitted parenterally; most cases are clinically inapparent or have mild flu-like symptoms; any jaundice is mild.
anicteric hepatitis  viral hepatitis without jaundice.
hepatitis B  an acute viral disease transmitted primarily parenterally, but also orally, by intimate personal contact, and from mother to neonate. Prodromal symptoms of fever, malaise, anorexia, nausea, and vomiting decline with the onset of clinical jaundice, angioedema, urticarial skin lesions, and arthritis. After 3 to 4 months most patients recover completely, but some may become carriers or remain ill chronically.
hepatitis C  a viral disease caused by the hepatitis C virus, commonly occurring after transfusion or parenteral drug abuse; it frequently progresses to a chronic form that is usually asymptomatic but that may involve cirrhosis.
cholangiolitic hepatitis  cholestatic h. (1).
cholestatic hepatitis 
1. inflammation of the bile ducts of the liver associated with obstructive jaundice.
2. hepatic inflammation and cholestasis resulting from reaction to drugs such as estrogens or chlorpromazines.
hepatitis D , delta hepatitis infection with hepatitis D virus, occurring either simultaneously with or as a superinfection in hepatitis B, whose severity it may increase.
hepatitis E  a type transmitted by the oral-fecal route, usually via contaminated water; chronic infection does not occur but acute infection may be fatal in pregnant women.
enterically transmitted non-A, non-B hepatitis  (ET-NANB) h. E.
hepatitis G  a post-transfusion disease caused by hepatitis G virus, ranging from asymptomatic infection to fulminant hepatitis.
infectious hepatitis  h. A.
infectious necrotic hepatitis  black disease.
lupoid hepatitis  chronic active hepatitis with autoimmune manifestations.
neonatal hepatitis  hepatitis of uncertain etiology occurring soon after birth and marked by prolonged persistent jaundice that may progress to cirrhosis.
non-A, non-B hepatitis  a syndrome of acute viral hepatitis occurring without the serologic markers of hepatitis A or B, including hepatitis C and hepatitis E.
posttransfusion hepatitis  viral hepatitis, now primarily hepatitis C, transmitted via transfusion of blood or blood products, especially multiple pooled donor products such as clotting factor concentrates.
serum hepatitis  h. B.
transfusion hepatitis  posttransfusion h.
viral hepatitis  h. A, h. B, h. C, h. D, and h. E.

neonatal hepatitis
n.
Hepatitis of unknown cause characterized by the onset of obstructive jaundice in the first few weeks of life and marked by hepatocyte degeneration and the appearance of multinucleated giant cells in the liver.

neonatal hepatitis,
hepatitis of unknown cause with onset in the first few weeks of life. Some cases are associated with viral or bacterial infection; a few are familial. It is characterized by the transformation of hepatocytes into polynuclear giant cells and by conjugated hyperbilirubinemia with jaundice. Most patients recover completely; some develop chronic disease or fatal cirrhosis. Also called giant cell hepatitis.

neonatal 'hepatitis'
A generic term for diseases of the newborn hepatic parenchyma, commonly associated with ↑ conjugated hyperbilirubinemia Diagnosis Requires ≥ 3 of following: fatty changes, cholestasis, bile duct proliferation, fibrosis, pseudoacini, cirrhosis Etiology Infection–syphilis, listeriosis, HBV, rubella, CMV, echovirus, adenovirus, toxoplasmosis, metabolic disease–α1-antitrypsin deficiency, cystic fibrosis, Wilson's disease, galactosemia, fructosuria, tyrosinemia, mechanical–choledochal cysts, intrahepatic ductal atresia hypoplasia, familial intrahepatic cholestasis, HDN, etc. See Hemolytic disease of the newborn. Cf Giant cell hepatitis.


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