neomycin


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neomycin

 [ne″o-mi´sin]
a broad-spectrum aminoglycosideantibiotic produced by Streptomyces fradiae, effective against a wide range of gram-negative bacilli and some gram-positive bacteria. It is used, as the sulfate salt, for urinary tract irrigation, administered orally to prepare the bowel for surgery, and applied to the skin, eyes, and ears to treat infections due to susceptible organisms. In topical preparations it is often combined with other antibiotics or antiinflammatory steroids.

neomycin

/neo·my·cin/ (-mi´sin) a broad-spectrum aminoglycoside antibiotic produced by Streptomyces fradiae, effective against a wide range of gram-negative bacilli and some gram-positive bacteria; used as the sulfate salt.

neomycin

(nē′ə-mī′sĭn)
n.
A broad-spectrum antibiotic produced from strains of the actinomycete Streptomyces fradiae and used especially in the form of its sulfate as an intestinal antiseptic in surgery.

neomycin

Infectious disease A broad-spectrum aminoglycoside antibiotic obtained from Streptomyces fradiae, which is generally effective against gram-negative rods and some gram-positive cocci

neomycin

An aminoglycoside antibiotic drug derived from a strain of Streptomyces fradiae . Neomycin can be given by mouth to destroy organisms in the bowel or can be used in solution to irrigate the bladder. It is poorly absorbed into the bloodstream. It is much too toxic to be given by injection and can have seriously damaging effects on hearing and on the kidneys. The drug is widely used as a surface application in ointments with other ingredients such as steroids. A brand name is Nivemycin. Preparations of neomycin with a corticosteroid, for external use, include Audicort, Betnovate-N, Dermovate-NN, Maxitrol, Neo-Cortef, Synalar-N, Tri-Adcortyl and Vistamethasone N. The drug is also formulated with the antibiotics polymyxin and gramicidin and with the antifungal drug nystatin.

neomycin (nē´ōmī´sin),

n an antibiotic secured from cultures of
S. fradiae, used for preoperative sterilization. It is a constituent of topically applied ointments, solutions, and troches because of its antibacterial action against gram-negative organisms.

neomycin

an aminoglycoside antibiotic produced by Streptomyces fradiae; the sulfate is used as an intestinal antiseptic and in treatment of systemic infections due to gram-negative bacteria. High doses and prolonged treatment can be nephrotoxic and ototoxic.

neomycin B
References in periodicals archive ?
A study performed in the 1990s reported that most MRSA strains were susceptible to bacitracin, and many were resistant to neomycin (8).
coli 27 Antibiotic + EEHM MIC (ng/ml) FIC index (type of interaction) EEHM 64 Amikacin 128 Kanamycin 128 Gentamicin 8 Neomycin 32 EEHM / amikacin 16 / 64 0.
But in case of tetracycline, norfloxacin, gentamicin, riphampicin, and neomycin all strains found to be 100% sensitive.
It would be interesting to note that when antibacterial study of cream, placebom neomycin and methanolic ectract of M.
Intermediate resistances to neomycin and streptomycin were also found but suggested a different resistance mechanism than the AME caused by apramycin exposure.
Therefore, the organisms most often causing otitis externa appear to be developing resistance to neomycin and polymyxin B but not to ofloxacin.
First isolated in the 1950s, several aminoglycoside antibiotics like neomycin were developed over the ensuing decades.
1% Spersadex Prednisolone acetate Pred Forte 18 - 36 40 1% Combined preparations Betamethasone, Betnesol N 36 - 54 neomycin Dexamethasone, Covomycin D 36 - 54 chloramphenicol Fluoromethalone, FML-Neo neomycin Dexamethasone, Maxitrol 36 -54 neomycin, polymyxin B Dexamethasone, Sofradex 36 - 54 framycetin, gramicidin Dexamethasone, Spersadex Comp 36 - 54 chloramphenicol Hydrocortisone, Terra-Cortril 8 - 12 oxytetracycline, polymixin B Dexamethasone, Tobradex 36 - 54 tobramycin Drugs in order of Side-effect Indications increasing potency Single preparations Worsening Allergic keratoconjunctivitis, Prednisolone acetate of external inflamed pterygium, 0.
April 4, 2011 /PRNewswire/ -- Breckenridge is announcing that it entered into an agreement with Oman Pharmaceutical Products Company LLC, of Salalah, Sultanate of Oman to market Neomycin Sulfate Tablets.
coli isolate (EC27) resistant to neomycin and gentamicin (low level) and to tobramycin, amikacin and kanamycin (13).
In addition, both strains were found to be d-tartrate-fermenting (dT+) biovars (4), susceptible to ampicillin, amoxicillin-clavulanic acid, cephalothin, ceftazidime, gentamicin, streptomycin, chloramphenicol, tetracycline, neomycin, nalidixic acid, norfloxacin, and ciprofloxacin and resistant to sulfamethoxazole and co-trimoxazole.