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neisserial

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neisserial [nīs-se´re-al]
of, relating to, or caused by Neisseria.


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Deficiency of the complement component, C3, leads to repeated sinopulmonary infections similar to agammaglobulinemia, while deficiencies in the terminal complement components (C6, C7, C8, C9) result in recurrent systemic infections or meningitis with neisserial organisms.
This study found that the Company's Neisserial porins, particularly PorB, are capable of inserting themselves into host cells thereby creating a potential mechanism to impede the initial phases of bacterial infection.
The most well-known example is the susceptibility of patients with terminal complement component deficiencies to neisserial infections.
 
 
 
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