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An unconscious defense mechanism used to allay anxiety by denying the existence of important conflicts, troublesome impulses, events, actions, or illness.
Synonym(s): negation
[M.E., fr, O.Fr., fr. L. denegare, to say no]


A denial, contradiction, or negative statement.


An unconscious defense mechanism used to allay anxiety by denying the existence of important conflicts or troublesome impulses.
Synonym(s): negation.
[M.E., fr, O.Fr., fr. L. denego, to say no]

Patient discussion about negation

Q. is her2 positive more agressive than her2 negative? i know someone with her2 positive breast cancer and her doctor said it was more difficult to detect upon its return if it came back i want to know if it is true and what can she do to detect it earlier

A. Over-expression of her2/neu, a specific molecule in the breast cancer cell is indeed considered to convey worse prognosis, and suggest the need for chemotherapy and immunotherapy with Herceptin. However, the decision is much more complicated and should be made on case by case basis after consulting a professional.

Q. Rising PSA to 10 with two negative biospies? Expect cancer? 67 yrs old in good health otherwise.

A. High values don't always mean it's cancer. At 67 years old, you're prostate is most likely enlarging, resulting in the higher PSA results. And after two negative biopsies, it sounds like you're in the clear. Like Brandon said though, keep up with your regular check ups.

Q. Does the cooking have a negative effect on the protein content of the food? I have heard that high temperatures cooking breaks the protein, so does the cooking have a negative effect on the protein content of the food?

A. Yes. Proteins can be denatured by heat, but only when the protein structure is delicate or is exposed to extremely high temperatures for long time. You must remember that breaking of protein is the physical-chemical process where the physical or chemical structure of a protein is rearranged. So cooking will not reduce on the nutritive value of the food until it’s cooked at cooking temperatures.

More discussions about negation
References in periodicals archive ?
I would also urge the Westminster Parliament not to allow the Conservative party in office for the time being not to seek to acquire Henry VIII's powers unto itself and so negate eons of democracy.
Clause 95 of the personal affairs law states that "Court may refer to scientific methods to negate fatherhood on condition that it was not admitted previously".
Scope: The estate also argues that the Tax Court erred in reviewing both the valid will and the N trust agreement to conclude that L intended to negate apportionment.
Bankruptcy does not negate the need for CPA services.
However, it would be highly disingenuous for Israeli, European or American architects and planners to celebrate and romanticize the built achievements of the European settlers of the 1930s in Tel Aviv, while overlooking and so condoning the ongoing systematic efforts of the Zionist project to negate, marginalize and destroy indigenous Palestinian culture.
Evil deeds done by some must never negate the good work done by others," she said.
This is not to negate the value of The Quiet Hand of God, which offers an impressive, unique collection of articles on one of the more significant forms of religious organization in the United States today.
This caused the crests and the troughs of the emissions from the star to negate each other, dimming the star's light and giving the astronomers a relatively unobstructed view of infrared emissions from the surrounding dust disk.
He added that he was troubled by the book's approach to sexual orientation, complaining that the book "tries to minimize or even negate that homosexuality is a problem.
Part I covers the early history of the National Park System, federal commissions that acquired Indian territory by forced land sales and nefarious policies intended to negate tribal land claims, and congressional actions from 1950 to 1980 to expand and develop parks at the expense of native sovereignty.
Peter Costello's "tax cuts" of 2000, which did no more than negate the effects of bracket-creep over a short period and which permitted further bracket-creep.
The SweepZone Technology Ultrasonic Cleaning System utilizes simple in-line connections that facilitate installation and negate the need for professional assistance.