sodium has also been shown to be of potential use in reducing high-dose inhaled steroid use.
Table 1 Topical ophthalmic medications available for the treatment of ocular allergy in the UK Medication Name Formulation Optometrist class availability Mast cell Sodium Sodium Entry level stabiliser Cromoglycate Cromoglycate 2% but in (non- maximum proprietary) pack size of 10mL Catacrom Sodium At least (Moorfields Cromoglycate 2% Additional Pharmceu- (single use) Supply level ticals) Rapitil Nedocromil
At least (Sanofi- Sodium 2% Additional Aventis) Supply level Alomide Lodoxamide 0.
5) in the nedocromil
group than in the placebo group (p=0.
2 centimeters, shorter in the group that received budesonide than in the patients who received nedocromil
Jones P and the Nedocromil
Sodium Quality of Life Study Group.
Another mast cell stabilizer frequently used to help control allergies is nedocromil
Cromolyn (Intal), nedocromil
(Tilade) and corticosteroids are examples of anti-inflammatory medications currently available to treat asthma.
Other CFC-based medications include the corticosteroids triamcinolone and flunisolide, the mast cell stabilizers cromolyn and nedocromil
, and the [beta]-agonists metaproterenol, pirbuterol, and combined albuterol-ipratropium.
The seven MDI drugs include: flunisolide (Forest's Aerobid), triamcinolone (Kos' Azmacort), metaproterenol (Boehringer Ingelheim's Alupent), pirbuterol (3M's Maxair), cromolyn (King's Intal), nedocromil
(King's Tilade) and the combination of albuterol and ipratropium (Boehringer's Combivent).
Additive effect of glucocorticoids and nedocromil
The main preventative nasal sprays contain cromoglycate or nedocromil
Although cromolyn and nedocromil
are category B, a Dutch metaanalysis of 24 studies on the effect of cromolyn on asthma in children concluded that there is insufficient evidence to support a beneficial effect of cromolyn (Thorax 55:913-20, 2000).