necrotizing vasculitis

Also found in: Dictionary, Thesaurus, Encyclopedia.


inflammation of a blood or lymph vessel; see arteritis, lymphangitis, and phlebitis. Called also angiitis.
Churg-Strauss vasculitis churg-strauss syndrome.
hypersensitivity vasculitis a group of systemic necrotizing vasculitides thought to represent hypersensitivity to an antigenic stimulus, such as a drug, infectious agent, or exogenous or endogenous protein; all disorders in this group involve the small vessels.
necrotizing vasculitis see systemic necrotizing vasculitis.
nodular vasculitis a chronic vasculitis of unknown etiology found predominantly below the knees, especially on the calves in young and middle-aged women, characterized by the presence of painful, reddish blue nodular lesions that may ulcerate, leaving scars, or resorb, leaving atrophic depressions. In the late stages, there is replacement of the subcutaneous fat by fibrosis and atrophy (wucher atrophy).
systemic necrotizing vasculitis any of a group of disorders characterized by inflammation and necrosis of blood vessels, occurring in a broad spectrum of cutaneous and systemic disorders. It includes Churg-Strauss syndrome, polyarteritis nodosa, the various kinds of hypersensitivity vasculitis, and other conditions. Called also necrotizing vasculitis.

necrotizing vasculitis

an inflammatory condition of blood vessels characterized by necrosis, fibrosis, and proliferation of the inner layer of the vascular wall. Some cases result in occlusion and infarction. Necrotizing vasculitis may occur in rheumatoid arthritis and is common in systemic lupus erythematosus, periarteritis nodosa, and progressive systemic sclerosis. The condition is usually treated with corticosteroids.

necrotizing vasculitis

vasculitis, caused by deposition of immune complexes within blood vessel walls; characteristic of rheumatoid disease; may cause digital or foot ulceration


causing necrosis; exuding a brown to green, putrid discharge containing tissue debris.

necrotizing epithelioma, necrotizing calcifying epithelioma
necrotizing hepatopancreatitis
disease of shrimps caused by a small obligate intracellular unidentified bacterium; subacute to chronic syndrome with cumulative mortality of up to 90%.
necrotizing panniculitis
multifocal, erythematous, nonpruritic cutaneous lesions which ulcerate in the center and discharge seropurulent exudate; identifiable on histopathological examination.
necrotizing scleritis
a rare eye lesion, inflammatory proliferation of the anterior sclera, in dogs.
necrotizing ulcerative gingivitis
see necrotizing ulcerative gingivitis.
necrotizing vasculitis
important feature of the Arthus reaction; damage to the endothelium results from deposition of immune complexes in the vessel wall, usually on the basement membrane of the endothelium.
References in periodicals archive ?
The organs affected varied even in this small set of animals, but all dogs had necrotizing vasculitis and hemorrhage, and all but 1 had lymphadenitis and granulomatous disease.
B19 infections in our cases are likely to be acute or acute on a chronic infection because of the presence of DNAemia which persisted for one month in first case who had also suffered from necrotizing vasculitis of the skin.
Laboratory tests, renal biopsies, and clinical evaluations by rheumatologists at the Mayo Clinic, the University of New Mexico, and in San Francisco, California, confirmed the diagnoses of microscopic polyangiitis, systemic necrotizing vasculitis, leukocytoclastic vasculitis, and glomerulonephritis with positive antineutrophil cytoplasmic antibodies (ANCA) perinuclear pattern (pANCA) and negative cytoplasmic pattern (cANCA).
The 2012 revised vasculitis nomenclature defines MPA as a necrotizing vasculitis with few or no immune complex deposits predominantly affecting small vessels with frequent necrotizing glomerulonephritis and pulmonary capillaritis.
Cutaneous necrotizing vasculitis induced by Levamisole.
Necrotizing vasculitis continues to be difficult to diagnose and treat.
Our specimen also did not contain any granulomas, intravascular thrombosis, necrotizing vasculitis, or lymphoid aggregates.
Histologically, necrotizing vasculitis and inflammation consisting of histiocytes, lymphocytes, plasma cells, and multinucleated giant cells surrounding geographic areas of basophilic necrosis are characteristic2,25-28 (Figure 2, A through D).
It is mainly used for the treatment and prophylaxis of gout and familial Mediterranean fever (FMF), (2) but colchicine also privides therapeutic efficacy for several diseases, including psoriasis, necrotizing vasculitis, Behet's syndrome, scleroderma, sarcoidosis, amyloidosis, and idiopathic pulmonary fibrosis.
Calciphylaxis: A condition mimicking necrotizing vasculitis.