necrotizing sialometaplasia


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nec·ro·tiz·ing si·a·lo·met·a·pla·si·a

squamous cell metaplasia of the salivary gland ducts and lobules, with necrosis of the salivary gland lobules; seen most frequently in the hard palate.

necrotizing sialometaplasia

Oral pathology A benign self-limited reactive salivary gland inflammation, which may clinically and histologically mimic malignancy–eg, mucoepidermoid carcinoma; most occur in minor salivary glands–SG; it may occur in SGs of the upper aerodigestive tract, or larynx DiffDx Mucoepidermoid carcinoma, SCC

necrotizing sialometaplasia

(sī″ă-lō-met″ă-plā′zh(ē-)ă) [ sialo- + metaplasia]
An ulcerative oral lesion usually found on the palate, caused by inflammation of the salivary glands. It may simulate an oral malignancy.

nec·ro·tiz·ing si·a·lo·met·a·pla·si·a

(nekrō-tīz-ing sīă-lō-met-ă-plāzē-ă)
Squamous cell metaplasia of the salivary gland ducts and lobules; seen most frequently in the hard palate.
[G. sialon, saliva, + metaplasia]
References in periodicals archive ?
We report a rare case of necrotizing sialometaplasia of the right lateral nasopharynx with extension into the right parapharyngeal space in a 39-year-old man.
I read with great interest the recent case reported by Carlson (1) on a bulimic patient presenting with necrotizing sialometaplasia (NSM) in the hard palate.
Necrotizing sialometaplasia after silastic ring vertical gastroplasty: case report and review of literature.
Necrotizing sialometaplasia accompanied by adenoid cystic carcinoma on the soft palate.
Necrotizing sialometaplasia (NSM) is a benign, self-healing lesion of salivary glands, which represents less than 1% of biopsied oral lesions.
Necrotizing sialometaplasia in the context of bulimia was first reported in 1998 in 2 patients and has since been reported in 5 and possibly 6 cases.
Necrotizing sialometaplasia is a benign, spontaneously healing inflammatory condition.
Necrotizing sialometaplasia is a benign inflammatory process that involves the minor salivary glands, primarily those of the hard palate.
MECs must be distinguished from necrotizing sialometaplasia, chronic sialadenitis, cystadenoma, cystadenocarcinoma, squamous cell carcinoma, epithelial-myoepithelial carcinoma, clear cell carcinoma (not otherwise specified), and metastatic tumors.
Necrotizing sialometaplasia is a benign, self-limited, reactive inflammatory process that involves salivary glands.
Necrotizing sialometaplasia most commonly arises in the minor salivary glands of the hard palate; other mucosal sites are affected less frequently.
1) In our patient, the differential diagnosis included (1) benign fibrous and neural tumors with secondary ulceration, (2) a specific infection, and (3) perhaps necrotizing sialometaplasia.

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