necrotizing fasciitis


Also found in: Dictionary, Acronyms, Encyclopedia, Wikipedia.
Related to necrotizing fasciitis: necrotizing enterocolitis

fasciitis

 [fas″e-i´tis]
inflammation of a fascia.
necrotizing fasciitis a fulminating group A streptococcal infection beginning with severe or extensive cellulitis that spreads to involve the superficial and deep fascia, producing thrombosis of the subcutaneous vessels and gangrene of the underlying tissues. A cutaneous lesion usually serves as a portal of entry for the infection, but sometimes no such lesion is found.
nodular fasciitis (proliferative fasciitis) a benign, reactive proliferation of fibroblasts in the subcutaneous tissues and commonly associated with the deep fascia.
pseudosarcomatous fasciitis a benign soft tissue tumor occurring subcutaneously and sometimes arising from deep muscle and fascia.

nec·ro·tiz·ing fas·ci·i·tis

a rare soft-tissue infection primarily involving the superficial fascia and resulting in extensive undermining of surrounding tissues; progress is often fulminant and may involve all soft-tissue components, including the skin; usually occurs postoperatively, after minor trauma, or after inadequate care of abscesses or cutaneous ulcers.
See also: group A streptococcal necrotizing fasciitis.

necrotizing fasciitis

n.
Severe, rapidly progressing infection of subcutaneous tissues by streptococci and other bacteria, marked by tissue necrosis and by pain, swelling, and heat in the affected area, usually following an injury or a surgical procedure.

necrotizing fasciitis

Necrotizing subcutaneous infection Infectious disease A rapidly progressive bacterial infection that spreads along fascial planes which, absent effective therapy–eg, debridement, results in skin breakdown with bleb and bulla formation, small vessel thrombosis and 2º necrosis, leading to subcutaneous anesthesia Agents Streptococci, gram-negative and mixed bacteria

necrotizing fasciitis

An uncommon but severe form of tissue damage caused by a streptococcus of Group A. There is widespread inflammation of the layer of fatty tissue under the skin and the effect is so intense that the tissue appears, in places, almost to be ‘eaten away’. The condition features severe pain, marked general upset and intense redness of the overlying skin. Surgical exploration shows grey, swollen fat that can be stripped out easily with the finger. Surgical shock and failure of various organs, such as the kidneys, may occur and the outcome, in inadequately managed or late treated cases is often fatal. Treatment is by massive doses of antibiotics, early radical surgery to remove infected tissue and exposure to high oxygen concentrations in a special chamber (see HYPERBARIC OXYGEN TREATMENT). Inadequate treatment results in a mortality of 30 to 60 per cent.

Necrotizing fasciitis

A destructive infection which follows severe cellulitis and involves the deep skin and underlying tissues.
Mentioned in: Cellulitis

necrotizing fasciitis

deep-seated, aggressive streptococcal infection of skin and subcuticular tissues, characterized by progressive tissue destruction or gangrene with possible loss of part/all the limb, unless treated promptly with appropriate antimicrobial therapies (e.g. drainage and antibiosis)

fasciitis

inflammation of a fascia.

necrotizing fasciitis
a gas-forming, fulminating, necrotic infection of the superficial and deep fascia, resulting in thrombosis of the subcutaneous vessels and gangrene of the underlying tissues. It is usually caused by multiple pathogens.
nodular fasciitis, proliferative fasciitis
see nodular fasciitis.
References in periodicals archive ?
Contact: Jacqueline Roemmele Executive Director National Necrotizing Fasciitis Foundation jroemmele@aol.
Necrotizing fasciitis complicated by fatal multiple organ dysfunction due to Pasteurella multocida infection: a case report.
Whereas most cases of cellulitis can be successfully managed by antibiotic therapy alone, necrotizing fasciitis must be managed more aggressively and requires extensive surgical resection in combination with high-dose IV antimicrobials [2-5].
Zygomycotic necrotizing fasciitis caused by Apophysomyces elegans.
Role of tissue oxygen saturation monitoring in diagnosing necrotizing fasciitis of the lower limbs.
Necrotizing fasciitis is a rare complication associated with colorectal malignancy.
In the wake of a 2005 report linking community-acquired MRSA to 14 cases of necrotizing fasciitis in the Los Angeles area, Dr.
It also aims at the microbes--sometimes called flesh-eating bacteria--responsible for necrotizing fasciitis.
Abstract: Fournier gangrene is a life-threatening necrotizing fasciitis of the perineal-scrotal area that occurs in diabetic males.
Jim McNeill, a fireman with the Royal Household at Windsor Castle, said he was lucky to be alive after contracting necrotizing fasciitis in his leg hours before setting off on the 685-mile trek.
I'm so blessed to be alive today,'' said Schuman, 63, who was accompanied by his wife of 40 years, Maxine, and the physicians who treated his life-threatening case of necrotizing fasciitis, better known as flesh- killing bacteria.
While many other types of bacteria can cause necrotizing fasciitis, most cases result from GAS.

Full browser ?